Announcements Trials
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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Myeloid 1Lymphoid 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Sarcoma 5Rhabdoid Tumor 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Sarcoma, Synovial 3Lymphoma, Non-Hodgkin 3Lymphoma, B-Cell 3Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Recurrence 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Mesothelioma 2Medulloblastoma 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Lymphoma, Mantle-Cell 1Lymphoma, B-Cell, Marginal Zone 1Inhibition, Psychological 1Hodgkin Disease 1

Interventions

Cyclophosphamide 82fludarabine phosphate 68Mycophenolic Acid 59Whole-Body Irradiation 52Peripheral Blood Stem Cell Transplantation 51Tacrolimus 49Melphalan 44Etoposide 42Busulfan 39fludarabine 36Rituximab 36Filgrastim 36Granulocyte Colony-Stimulating Factor 35Brentuximab Vedotin 33Cyclosporine 32Doxorubicin 28Methotrexate 27Antilymphocyte Serum 27Radiotherapy 24Dacarbazine 19Vinblastine 18Nivolumab 18Cytarabine 18Prednisone 16Carmustine 16thymoglobulin 15Stem Cell Transplantation 15Sirolimus 15Alemtuzumab 14Vincristine 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Hodgkin Disease × tazemetostat × Clear all
NCT03213665 2026-04-13

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

Phase 2 Completed
20 enrolled 12 charts
CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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