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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 1

Conditions

Colorectal Neoplasms 28Colonic Neoplasms 19Rectal Neoplasms 17Neoplasm Metastasis 16Cholangiocarcinoma 10Stomach Neoplasms 9Neoplasms 4Liver Neoplasms 4Carcinoma, Hepatocellular 4Esophageal Neoplasms 3Pancreatic Neoplasms 2Gastrointestinal Stromal Tumors 2Cirrhosis, Familial, with Pulmonary Hypertension 2Bile Duct Neoplasms 2Appendiceal Neoplasms 2Adenocarcinoma Of Esophagus 2Vipoma 1Stage IV Fallopian Tube Cancer AJCC v6 and v7 1Somatostatinoma 1Resected Liver Metastases From Colorectal Cancer 1Pseudomyxoma Peritonei 1Pheochromocytoma 1Ovarian Neoplasms 1Neuroblastoma 1Neoplasms, Unknown Primary 1Nasopharyngeal Carcinoma 1Insulinoma 1Hyperthermia 1Glucagonoma 1Genetic Diseases, Inborn 1

Interventions

Diathermy 20Radiotherapy 10Cisplatin 5Fluorouracil 4Drug Therapy 4Radiation 3Melphalan 3Immune Checkpoint Inhibitors 3Cytoreduction Surgical Procedures 3Brachytherapy 3tislelizumab 2Solutions 2Immunotherapy 2Hyperthermia, Induced 2Hydrogen Peroxide 2Doxorubicin 2Conization 2Capecitabine 2spartalizumab 1sodium thiosulfate 1anlotinib 1Temozolomide 1Surgical Procedures, Operative 1Saline Solution 1Radiation Dose Hypofractionation 1Paclitaxel 1Oxaliplatin 1Mitomycin 1Leucovorin 1Laser Therapy 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Hyperthermia × Floxuridine × Clear all
NCT00001576 2008-03-04

A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
28 enrolled
Gastrointestinal

Hyperthermia, Liver Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

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