Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 2Sarcoma 1Dermatologic 1

Conditions

Multiple Myeloma 154Lymphoma 78Lymphoma, Non-Hodgkin 62Neoplasms, Plasma Cell 54Leukemia 52Leukemia, Myeloid, Acute 49Hodgkin Disease 48Precursor Cell Lymphoblastic Leukemia-Lymphoma 45Leukemia, Lymphocytic, Chronic, B-Cell 45Myelodysplastic Syndromes 42Lymphoma, Large B-Cell, Diffuse 41Lymphoma, Follicular 40Lymphoma, Mantle-Cell 38Lymphoma, Large-Cell, Immunoblastic 29Neuroblastoma 27Burkitt Lymphoma 27Lymphoma, B-Cell, Marginal Zone 26Recurrence 22Immunoglobulin Light-chain Amyloidosis 22Myeloproliferative Disorders 18Leukemia, Myeloid, Accelerated Phase 16Hematologic Neoplasms 16Congenital Abnormalities 16Leukemia, Myeloid, Chronic-Phase 14Leukemia, Myelogenous, Chronic, BCR-ABL Positive 14Graft vs Host Disease 14Dendritic Cell Sarcoma, Interdigitating 14Waldenstrom Macroglobulinemia 13Leukemia, Myelomonocytic, Chronic 13Blast Crisis 13

Interventions

Melphalan 3Diathermy 2Cytoreduction Surgical Procedures 2Conization 2tislelizumab 1spartalizumab 1sodium thiosulfate 1Radiotherapy 1Leucovorin 1Laparotomy 1Immune Checkpoint Inhibitors 1Fluorouracil 1Floxuridine 1Drug Therapy 1Cryotherapy 1Cisplatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Hyperthermia × Melphalan × Clear all
NCT00001576 2008-03-04

A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
28 enrolled
Gastrointestinal

Hyperthermia, Liver Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT00001577 2008-03-04

Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
30 enrolled
DermatologicSarcoma

Hyperthermia, Melanoma, Sarcoma

NCT00001587 2008-03-04

A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
30 enrolled
Gastrointestinal

Hyperthermia, Liver Neoplasms, Neoplasm Metastasis

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