Clinical Trials Browser

INDUSTRY × Interventional × Hypoxia × Clear all

NCT02174549 2026-04-20

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

Phase 1/2 Recruiting

EndocrineGastrointestinalNET

Hypoxia, Carcinoma, Hepatocellular, Neuroendocrine Tumors

NCT06685848 2026-01-07

Comparison of Hemanext ONE® System and Conventional Red Blood Cell Transfusion

Phase NA Recruiting

Other hematologic neoplasm

Hypoxia, Hematologic Neoplasms

NCT05119335 2025-11-12

A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Phase 1/2 Terminated

Hypoxia, Carcinoma, Renal Cell, Kidney Neoplasms

NCT02449681 2023-01-12

Study for Treatment of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Skin

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck, Hypoxia, Carcinoma, Squamous Cell

NCT02454842 2023-01-12

TH-4000

Phase 2 Terminated

Hypoxia, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell

NCT01924689 2019-09-09

Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies

Phase 1 Completed

24 enrolled 18 charts

Hypoxia, Chordoma, Necrosis, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT03098160 2017-10-30

Immunotherapy Study of Evofosfamide in Combination With Ipilimumab

Phase 1 Unknown

DermatologicGastrointestinalGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Hypoxia, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT01522872 2016-06-02

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

Phase 1/2 Unknown

Hypoxia, Multiple Myeloma, Neoplasms, Plasma Cell

NCT01118819 2016-01-20

Safety Study of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies

Phase 1 Terminated

Hypoxia, Necrosis, Neoplasm Metastasis, Neoplasms

NCT00743379 2015-05-07

Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors

Phase 1/2 Completed

GastrointestinalGenitourinaryThoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Prostatic Neoplasms

NCT01075399 2013-08-30

HX4-200

Phase 2 Completed

50 enrolled 7 charts

GastrointestinalGynecologicHead & NeckThoracic

Hypoxia, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Rectal Neoplasms

NCT01213030 2012-09-25

Clinical Evaluation of the New Hypoxia Imaging Agent HX4

Phase 1/2 Completed

GastrointestinalHead & NeckThoracic

Hypoxia, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms

NCT00495144 2012-07-27

A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors

Phase 1 Completed

Hypoxia, Neoplasms

NCT00884520 2010-03-16

VM4-037

Phase EARLY_PHASE1 Completed

GastrointestinalGenitourinaryHead & NeckThoracic

Hypoxia, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms

NCT00090727 2006-11-02

Chemotherapy for Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Unknown

BreastGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasm

Hypoxia, Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute