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Phase

Phase 2 3Phase 3 1

Status

Recruiting 2Completed 2

Sponsor Class

OTHER 42INDUSTRY 11NETWORK 4OTHER_GOV 2NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Plasma cell 4Other 1Gastrointestinal 1

Conditions

Breast Neoplasms 49Prostatic Neoplasms 38Carcinoma, Non-Small-Cell Lung 28Neoplasms 24Precursor Cell Lymphoblastic Leukemia-Lymphoma 23Multiple Myeloma 22Lymphoma 21Leukemia, Myeloid, Acute 17Colorectal Neoplasms 17Melanoma 15Lung Neoplasms 13Hodgkin Disease 11Brain Neoplasms 11Medulloblastoma 10Lymphoma, Non-Hodgkin 10HIV Infections 10Glioblastoma 10Squamous Cell Carcinoma of Head and Neck 9Pancreatic Neoplasms 9Neoplasm Metastasis 9Leukemia, Biphenotypic, Acute 9Leukemia 9Head and Neck Neoplasms 9Neuroblastoma 8Hematologic Neoplasms 8Ependymoma 8Glioma 7Carcinoma, Renal Cell 7Astrocytoma 7Wilms Tumor 6

Interventions

isatuximab 1dexamethasone acetate 1dexamethasone 21-phosphate 1daratumumab 1belantamab mafodotin 1auricularum 1Stem Cell Transplantation 1Specimen Handling 1Melphalan 1Magnetic Resonance Spectroscopy 1Dexamethasone 1Cyclophosphamide 1Calcium Dobesilate 1Bortezomib 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
NETWORK × Immunoglobulin Light-chain Amyloidosis × 1 year × Clear all
NCT06022939 2026-05-06

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

SWOG Cancer Research Network

Phase 3 Recruiting
338 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT06649695 2026-04-21

A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis

European Myeloma Network B.V.

Phase 2 Recruiting
30 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT03499808 2025-09-09

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

SWOG Cancer Research Network

Phase 2 Completed
43 enrolled 23 charts
GastrointestinalOtherPlasma cell

Lymphadenopathy, Immunoglobulin Light-chain Amyloidosis, Constipation, Diarrhea, Gastrointestinal Hemorrhage, Hepatomegaly, Macroglossia, Nausea, Purpura

NCT04617925 2025-09-05

EMN27

European Myeloma Network B.V.

Phase 2 Completed
35 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

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