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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1

Conditions

Rhabdoid Tumor 6Wilms Tumor 5Sarcoma 5Osteosarcoma 5Neuroectodermal Tumors, Primitive, Peripheral 5Neuroblastoma 5Medulloblastoma 5Lymphoma, Non-Hodgkin 5Histiocytosis, Langerhans-Cell 5Hepatoblastoma 5Glioma 5Ependymoma 5Rhabdomyosarcoma 4Central Nervous System Neoplasms 4Neoplasm Metastasis 3Sarcoma, Ewing 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Neuroendocrine Tumors 2Lung Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Xanthogranuloma, Juvenile 1Thyroid Cancer, Papillary 1Ovarian Neoplasms 1Non functioning pancreatic endocrine tumor 1Nasopharyngeal Carcinoma 1Multiple Myeloma 1Lymphoma 1Immunoglobulin Light-chain Amyloidosis 1Histiocytic Sarcoma 1

Interventions

dexamethasone acetate 2dexamethasone 21-phosphate 2auricularum 2Specimen Handling 2Magnetic Resonance Spectroscopy 2Dexamethasone 2Calcium Dobesilate 2Biopsy 24-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene 2venetoclax 1ixazomib 1daratumumab 1belantamab mafodotin 1X-Rays 1Stem Cell Transplantation 1Phantoms, Imaging 1Melphalan 1Cyclophosphamide 1Bortezomib 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Immunoglobulin Light-chain Amyloidosis × Phantoms, Imaging × 30 days × Clear all
NCT04847453 2026-05-13

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

National Cancer Institute (NCI)

Phase 1 Active not recruiting
24 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

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