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Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Plasma cell 2

Conditions

Prostatic Neoplasms 10Wilms Tumor 9Leukemia, Myeloid, Acute 9Osteosarcoma 8Neuroblastoma 8Neoplasm Metastasis 8Multiple Myeloma 8Lung Neoplasms 8Glioma 8Sarcoma 7Rhabdoid Tumor 7Lymphoma, Non-Hodgkin 7Hepatoblastoma 7Carcinoma, Hepatocellular 7Rhabdomyosarcoma 6Neuroectodermal Tumors, Primitive, Peripheral 6Myelodysplastic Syndromes 6Medulloblastoma 6Lymphoma 6Histiocytosis, Langerhans-Cell 6Ependymoma 6Colorectal Neoplasms 6Breast Neoplasms 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Melanoma 5Central Nervous System Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Sarcoma, Ewing 4Ovarian Neoplasms 4Endometrial Neoplasms 4

Interventions

Dexamethasone 7Bortezomib 6Cyclophosphamide 5daratumumab 3Specimen Handling 34-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene 3venetoclax 2dexamethasone acetate 2dexamethasone 21-phosphate 2belantamab mafodotin 2auricularum 2X-Rays 2Phantoms, Imaging 2Magnetic Resonance Spectroscopy 2Clinical Protocols 2Calcium Dobesilate 2Biopsy 2ixazomib 1Tissue Banks 1Stem Cell Transplantation 1Pharmaceutical Preparations 1Melphalan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Immunoglobulin Light-chain Amyloidosis × X-Rays × 90 days × Clear all
NCT04847453 2026-05-13

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

National Cancer Institute (NCI)

Phase 1 Active not recruiting
24 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT05898646 2026-03-30

Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

Mayo Clinic

Phase 2 Recruiting
96 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

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