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Phase

Phase 2 8Phase 1 5Phase 1/2 3Phase 3 2

Status

Withdrawn 1Recruiting 1Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Plasma cell 3

Conditions

Multiple Myeloma 44Recurrence 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Neoplasms, Plasma Cell 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Non-Hodgkin 3Lymphoma, Mantle-Cell 3Lymphoma 3Lung Neoplasms 3Leukemia 3Immunoglobulin Light-chain Amyloidosis 3Amyloidosis 3Myelodysplastic Syndromes 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myeloid, Acute 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Smoldering Multiple Myeloma 1Small Cell Lung Carcinoma 1Rectal Neoplasms 1Proteostasis Deficiencies 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Oropharyngeal Neoplasms 1Neoplasms 1Melanoma 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphodepleting Chemotherapy 1

Interventions

Dexamethasone 7daratumumab 3Peripheral Blood Stem Cell Transplantation 3Calcium Dobesilate 3venetoclax 2pomalidomide 2ixazomib 2fludarabine phosphate 2Whole-Body Irradiation 2Mycophenolic Acid 2Lenalidomide 2Cyclosporine 2Cyclophosphamide 2ethanolamine oleate 1dexamethasone acetate 1carfilzomib 1birtamimab 1belantamab mafodotin 1Trimethoprim, Sulfamethoxazole Drug Combination 1Trimethoprim 1Thalidomide 1Sulfamethoxazole 1Sodium Chloride 1Saline Solution, Hypertonic 1Saline Solution 1Phenytoin 1Pentetic Acid 1Methotrexate 1Melphalan 1In Situ Hybridization, Fluorescence 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Immunoglobulin Light-chain Amyloidosis × Calcium Dobesilate × Clear all
NCT05451771 2025-07-08

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

Columbia University

Phase 1/2 Recruiting
53 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Proteostasis Deficiencies

NCT05486481 2025-03-06

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

University of California, San Francisco

Phase 1/2 Withdrawn
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT02545907 2021-04-15

CATALYST

University College, London

Phase 1/2 Completed
10 enrolled 14 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

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