Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 6Completed 2Withdrawn 1Unknown 1Terminated 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Plasma cell 2

Conditions

Multiple Myeloma 55Recurrence 6Neoplasms, Plasma Cell 3Plasmacytoma 2Neoplasms 2Lymphoma, Non-Hodgkin 2Leukemia, Myeloid, Acute 2Immunoglobulin Light-chain Amyloidosis 2Carcinoma, Non-Small-Cell Lung 2Waldenstrom Macroglobulinemia 1Various Advanced Cancer 1Urologic Neoplasms 1Triple Negative Breast Neoplasms 1Smoldering Multiple Myeloma 1Prostatic Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Personal Satisfaction 1Patient Satisfaction 1Patient Preference 1Pancreatic Neoplasms 1Non-small Cell Lung Cancer With STK11/LKB1 Mutation 1Myelodysplastic Syndromes 1Microsatellite Unstable Colorectal Cancer 1Lymphoma 1Leukemia, Myeloid 1Leukemia, Monocytic, Acute 1Hodgkin Disease 1Carcinoma, Renal Cell 1Amyloidosis 1Acute Kidney Injury 1

Interventions

Dexamethasone 27Melphalan 22Cyclophosphamide 15Peripheral Blood Stem Cell Transplantation 14Filgrastim 13Bortezomib 12Calcium Dobesilate 9Lenalidomide 7fludarabine phosphate 6Whole-Body Irradiation 5Mycophenolic Acid 5Cyclosporine 5Thalidomide 4Interferon-alpha 4Etoposide 4Busulfan 4miridesap 3dexamethasone acetate 3Radiotherapy 3Epoetin Alfa 3Doxycycline 3Darbepoetin alfa 3Carboplatin 3pomalidomide 2liposomal amphotericin B 2ixazomib 2daratumumab 2birtamimab 2Thiotepa 2Tacrolimus 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Immunoglobulin Light-chain Amyloidosis × daratumumab × Clear all
NCT04304144 2025-03-05

A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

Alexion Pharmaceuticals, Inc.

Phase 2 Completed
25 enrolled 14 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT02841033 2021-05-07

Daratumumab for the Treatment of Patients With AL Amyloidosis

Boston Medical Center

Phase 1/2 Completed
22 enrolled 10 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis

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