Announcements Trials
Browse Landscape

Phase

Phase 1 11Phase 2 7Phase 3 6Phase 1/2 4

Status

Terminated 2Not yet recruiting 2Completed 2Active not recruiting 1

Sponsor Class

OTHER 48NETWORK 8INDUSTRY 7NIH 4

Study Type

Interventional 7

Sponsor

Cancer Type

Plasma cell 7

Conditions

Carcinoma, Non-Small-Cell Lung 687Breast Neoplasms 585Neoplasms 468Colorectal Neoplasms 300Prostatic Neoplasms 263Neoplasm Metastasis 257Melanoma 242Ovarian Neoplasms 228Recurrence 216Lung Neoplasms 203Multiple Myeloma 196Lymphoma, Non-Hodgkin 155Pancreatic Neoplasms 154Leukemia, Myeloid, Acute 142Carcinoma, Hepatocellular 141Stomach Neoplasms 137Lymphoma 131Carcinoma, Renal Cell 128Glioblastoma 118Squamous Cell Carcinoma of Head and Neck 113Head and Neck Neoplasms 113Lymphoma, Follicular 106Leukemia, Lymphocytic, Chronic, B-Cell 99Small Cell Lung Carcinoma 96Lymphoma, Large B-Cell, Diffuse 96Leukemia 96Brain Neoplasms 91Carcinoma 82Uterine Cervical Neoplasms 77Triple Negative Breast Neoplasms 73

Interventions

birtamimab 3Dexamethasone 2Bortezomib 2daratumumab 1belantamab mafodotin 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 2 × INDUSTRY × Immunoglobulin Light-chain Amyloidosis × Clear all
NCT05951049 2026-05-06

A Study of AT-02 in Subjects With Systemic Amyloidosis.

Attralus, Inc.

Phase 2 Active not recruiting
120 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT07224672 2026-03-17

ALANIS

GlaxoSmithKline

Phase 2 Not yet recruiting
60 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT07055724 2025-07-09

Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis

Nanjing IASO Biotechnology Co., Ltd.

Phase 2 Not yet recruiting
17 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT04304144 2025-03-05

A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

Alexion Pharmaceuticals, Inc.

Phase 2 Completed
25 enrolled 14 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT02613182 2019-05-16

OLE

Prothena Biosciences Ltd.

Phase 2 Terminated
34 enrolled 10 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT02632786 2019-04-05

PRONTO

Prothena Biosciences Ltd.

Phase 2 Completed
129 enrolled 18 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Alzheimer Disease, Amyloidosis, Paraproteinemias

NCT03154047 2019-03-26

Study in Subjects With Light Chain (AL) Amyloidosis

Prothena Biosciences Ltd.

Phase 2 Terminated
80 enrolled 9 charts
Plasma cell

Immunoglobulin Light-chain Amyloidosis

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