Clinical Trials

Phase NA Active not recruiting

Insulinoma

NCT05735912 2026-01-13

ERASIN-RCT

60 enrolled

Insulinoma

NCT05088798 2025-12-19

18FDOPA HI

Phase 2 Recruiting

100 enrolled

Hyperinsulinism, Hypoglycemia, Infant, Newborn, Diseases, Insulinoma, Glucose Metabolism Disorders

NCT07272187 2025-12-09

EURAGIL

Recruiting

138 enrolled

CNSDermatologicEndocrineNETThoracic

Hyperaldosteronism, Insulinoma

NCT07262970 2025-12-04

Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a Tumor

Available

EndocrineNETSarcoma

Fibrosarcoma, Hyperinsulinism, Hypoglycemia, Insulinoma, Adenoma, Islet Cell, Liposarcoma, Neoplasms, Neuroectodermal Tumors, Primitive, Neuroendocrine Tumors

NCT03583528 2025-06-13

DOTATOC PET/CT for Imaging NET Patients

Active not recruiting

800 enrolled

Carcinoid Tumor, Vipoma, Ganglioneuroma, Glucagonoma, Insulinoma, Medulloblastoma, Meningioma, Neuroblastoma, Paraganglioma, Pheochromocytoma, Pituitary Neoplasms, Carcinoma, Merkel Cell, Gastrinoma, Carcinoma, Medullary, Neuroendocrine Tumors, Small Cell Lung Carcinoma

NCT01916148 2025-04-02

18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia

Available

Beckwith-Wiedemann Syndrome, Hyperinsulinism, Hypoglycemia, Insulinoma, Congenital Hyperinsulinism

NCT06725693 2025-02-11

Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease

Recruiting

500 enrolled

DermatologicEndocrineGenitourinaryThoracic

Insulinoma, Neoplasms

NCT00655655 2024-08-21

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

96 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Glucagonoma, Insulinoma, Melanoma, Pheochromocytoma, Somatostatinoma, Carcinoma, Merkel Cell, Gastrinoma, Carcinoma, Islet Cell, Carcinoma, Medullary

NCT02021604 2024-07-16

Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma

Phase 1 Recruiting

250 enrolled

Hyperinsulinism, Hypoglycemia, Insulinoma, Congenital Hyperinsulinism

NCT01525082 2024-02-06

Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors

EndocrineGastrointestinal

20 enrolled 15 charts

Glucagonoma, Insulinoma, Pancreatic Neoplasms, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT04452396 2023-12-12

CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Phase NA Terminated

7 enrolled

Hypoglycemia, Insulin Resistance, Insulinoma

NCT05523778 2023-11-02

A Multi-center Study to Evaluate the Efficacy and Safety of Pancreatic Duct Stents Placement Before the Enucleation of Insulinoma Located in the Head and Neck of the Pancreas Near the Main Pancreatic Duct

Phase NA Unknown

78 enrolled

Insulinoma

NCT04979611 2023-09-21

The Clinical Application of 68Ga-NOTA-exendin-4 PET/CT in Detecting Insulinoma

Phase 1 Unknown

60 enrolled

EndocrineGastrointestinalNET

Insulinoma

NCT00227617 2023-05-22

Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors

Phase 2/3 Terminated

36 enrolled 14 charts

EndocrineNETThoracic

Vipoma, Glucagonoma, Insulinoma, Adenoma, Islet Cell, Lung Neoplasms, Neoplasms, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell, Neuroendocrine Tumors

NCT02431715 2023-02-21

18F-FDOPA PET in Neuroendocrine Tumours

No longer available

CNSEndocrineHead & Neck

Thyroid cancer, medullary, Carcinoid Tumor, Insulinoma, Neuroblastoma, Paraganglioma, Pheochromocytoma

NCT04915144 2023-02-21

177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETs

Phase 2 Withdrawn

Gastro-enteropancreatic neuroendocrine tumor, Carcinoid Tumor, Vipoma, Insulinoma, Gastrinoma, Neuroendocrine Tumors

NCT05034783 2022-10-14

[68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients

Phase EARLY_PHASE1 Unknown

Insulinoma

NCT02259725 2021-12-15

Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors

3 enrolled 7 charts

Glucagonoma, Insulinoma, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT03189953 2021-06-16

GLP-1-AHH

Phase 1/2 Completed

56 enrolled

Insulinoma

NCT03053284 2021-05-14

Pasireotide in Hyperinsulinemic Hypoglycemia

Phase 2 Withdrawn

Hyperinsulinism, Insulinoma, Congenital Hyperinsulinism

NCT04741152 2021-02-05

Blinded Resection in Case of the Pancreatic Insulinoma

Completed

197 enrolled

Phase EARLY_PHASE1 Unknown

Insulinoma

NCT04185350 2019-12-04

Clinical Evaluation of 68Ga-NOTA-MAL-Cys39-exendin-4 Positron Emission Tomography in the Detection of Insulinoma

60 enrolled

Insulinoma

NCT03930368 2019-04-29

Application of Raw Corn Starch on Patients With Insulinoma

Phase NA Unknown

EndocrineGastrointestinal

Insulinoma, Congenital Hyperinsulinism

NCT01056601 2017-12-28

Panobinostat & Bortezomib in Pancreatic Cancer Progressing on Gemcitabine Therapy

Phase 2 Terminated

7 enrolled 8 charts

Glucagonoma, Insulinoma, Pancreatic Neoplasms, Somatostatinoma

NCT02831179 2017-09-28

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Phase 1 Withdrawn

DermatologicEndocrineGastrointestinalNET

Non functioning pancreatic endocrine tumor, Adrenal Cortex Neoplasms, Carcinoid Tumor, Vipoma, Glucagonoma, Insulinoma, Pheochromocytoma, Somatostatinoma, Zollinger-Ellison Syndrome, Carcinoma, Merkel Cell, Carcinoma, Medullary, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Multiple Endocrine Neoplasia Type 2b

NCT00730483 2017-08-25

Doxorubicin Beads in Treating Patients With Unresectable Liver Metastases From Neuroendocrine Tumors

Phase NA Terminated

13 enrolled 5 charts

Glucagonoma, Insulinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT02108782 2017-07-19

Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors

Phase 2 Withdrawn

BreastEndocrineGenitourinaryOther

Glucagonoma, Insulinoma, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT02273752 2017-02-03

Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer

Phase 2 Terminated

2 enrolled 5 charts

Breast Neoplasms, Carcinoma, Renal Cell, Glucagonoma, Insulinoma, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell, Mucositis

NCT00049023 2016-06-21

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Phase 1 Completed

27 enrolled

CNSEndocrineSarcoma

Familial ependymoma, Insulinoma, Adenoma, Islet Cell, Medulloblastoma, Neuroblastoma, Pheochromocytoma, Sarcoma, Gastrinoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Carcinoma, Islet Cell

NCT00416767 2016-05-30

Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery

Phase EARLY_PHASE1 Unknown

Vipoma, Glucagonoma, Insulinoma, Adenoma, Islet Cell, Neoplasms, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT02560376 2015-09-25

68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis

100 enrolled

Insulinoma, Nesidioblastosis

NCT00937079 2015-01-09

Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients

Completed

30 enrolled

CNSDermatologicEndocrineGenitourinaryHead & NeckThoracic

Hyperinsulinism, Hypoglycemia, Insulinoma

NCT00002947 2014-07-02

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Phase 1 Terminated

35 enrolled

Uveal Melanoma, Carcinoma, Renal Cell, Vipoma, Glucagonoma, Head and Neck Neoplasms, Insulinoma, Adenoma, Islet Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pheochromocytoma, Somatostatinoma, Carcinoma, Merkel Cell, Gastrinoma, Central Nervous System Neoplasms, Carcinoma, Islet Cell, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT02121366 2014-04-23

EUS

Phase NA Unknown

50 enrolled

Insulinoma

NCT00027638 2013-06-18

Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors