Announcements Trials
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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other solid neoplasm 1

Conditions

Carcinoma, Non-Small-Cell Lung 9Lung Neoplasms 7Neoplasms 3Neoplasm Metastasis 3Colorectal Neoplasms 2Advanced Solid Tumors 2Pancreatic Neoplasms 1Ovarian Neoplasms 1Non Small Lung Cancer 1Mesothelioma 1KRAS p.G12C Mutant Advanced Solid Tumors 1KRAS p, G12c Mutated /Advanced Metastatic NSCLC 1Fallopian Tube Neoplasms 1Endometrial Neoplasms 1Brain Neoplasms 1Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation 1Advanced Solid Tumor 1

Interventions

sotorasib 1Midazolam 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
KRAS p.G12C Mutant Advanced Solid Tumors × sotorasib × 90 days × Clear all
NCT03600883 2026-03-16

A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

Amgen

Phase 1/2 Active not recruiting
713 enrolled 1 FDA
Other solid neoplasm

KRAS p.G12C Mutant Advanced Solid Tumors

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