Clinical Trials Browser

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06819228 2025-10-03

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

Phase EARLY_PHASE1 Recruiting

18 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Mouth Neoplasms, Tongue Neoplasms

NCT06915454 2025-10-03

High-Resolution PET-CT Imaging for Surgical Margin Visualization

Phase NA Recruiting

50 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Mouth Neoplasms, Neoplasms, Tongue Neoplasms

NCT03340896 2025-09-02

SALTORL

Phase 3 Active not recruiting

256 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT06078527 2025-07-23

Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort

Phase NA Not yet recruiting

40 enrolled

Head & Neck

Globus Sensation, Laryngeal Diseases, Vocal Cord Paralysis, Dysphonia

NCT03529422 2025-07-20

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

Phase 2 Active not recruiting

18 enrolled 10 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Laryngeal Diseases, Mouth Neoplasms

NCT03854032 2025-06-06

Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck

Phase 2 Active not recruiting

45 enrolled

Head & Neck

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases

NCT03109873 2025-04-30

Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

Phase EARLY_PHASE1 Completed

9 enrolled 6 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Laryngeal Diseases

NCT03162731 2025-04-29

Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients With Stage III-IVB Head and Neck Cancer

Phase EARLY_PHASE1 Completed

24 enrolled

Head & Neck

Lymphoid Interstitial Pneumonia, Laryngeal Diseases

NCT05784012 2025-03-13

RADIAN

Phase 1/2 Recruiting

34 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT01693718 2024-01-29

A Multicenter Study of Intensive Concomitant Chemoradiotherapy With Filgrastim (GCSF) for Patients With Locoregionally Advanced Head and Neck Cancer

Phase 2 Completed

44 enrolled

Head & Neck

Laryngeal Diseases, Neoplasms

NCT01172470 2023-11-29

Phase II Trial of Pemetrexed-Based Induction Chemotherapy Followed by Concomitant Chemoradiotherapy in Previously Irradiated Head and Neck Cancer Patients

Phase 2 Completed

34 enrolled

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT01185158 2023-11-29

A Phase II Study of 250-mg ZD1839 Monotherapy in Recurrent or Metastatic or Both Recurrent and Metastatic Squamous Cell Carcinoma

Phase 2 Completed

46 enrolled

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT02892487 2023-11-18

RORC

Phase NA Terminated

183 enrolled

Head & Neck

Deglutition Disorders, Head and Neck Neoplasms, Laryngeal Diseases

NCT01185171 2023-05-11

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer

Phase 2 Completed

70 enrolled 11 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT03737968 2023-03-21

Window of Opportunity Trial of Durvalumab (MEDI4736) or Durvalumab/Tremelimumab as Neoadjuvant Chemotherapy to Identify Immune Dynamics in Surgically Resectable Head and Neck Cancer Patients.

Phase 2 Unknown

48 enrolled

Head & Neck

Laryngeal Diseases

NCT02126969 2023-03-13

A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN

Phase 2 Completed

45 enrolled 13 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases, Neoplasms

NCT02158234 2023-01-19

Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck

Phase 1 Completed

20 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases

NCT05679856 2023-01-11

VC-Larynx

Phase NA Unknown

50 enrolled

Head & Neck

Laryngeal Diseases, Laryngeal Neoplasms

NCT04777474 2022-12-07

Benefit of Enhanced Contact Endoscopy in Pre-histological Diagnosis of Laryngeal and Hypopharyngeal Mucosal Lesions

Phase NA Unknown

150 enrolled

Head & Neck

Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms

NCT01884259 2022-05-26

HNO-2

Phase 2 Completed

100 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT01326923 2020-10-09

Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer

Phase 2 Terminated

7 enrolled 5 charts

Head & Neck

Laryngeal Diseases

NCT02236936 2020-05-01

AGMT_HNO_PN

Phase 3 Terminated

8 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Hyperphagia, Laryngeal Diseases

NCT00534729 2019-03-01

Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA

Phase NA Completed

200 enrolled

Head & Neck

Hypopharyngeal Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms

NCT02035735 2018-12-11

Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers

Phase NA Completed

93 enrolled

Head & Neck

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Laryngeal Diseases

NCT01540682 2018-08-29

MLN8237 in Head and Neck Cancer

Phase 1 Completed

9 enrolled

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases

NCT02926573 2018-08-08

GABA

Phase 4 Completed

123 enrolled 13 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases, Pain, Postoperative, Acute Pain

NCT02540928 2018-07-18

AMG 319 in HPV Positive and Negative HNSCC

Phase 2 Terminated

35 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT01843673 2016-07-06

Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer

Phase NA Completed

16 enrolled 9 charts

Head & Neck

Lymphoid Interstitial Pneumonia, Head and Neck Neoplasms, Laryngeal Diseases

NCT01287390 2016-01-27

Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck

Phase 2 Completed

100 enrolled

Head & Neck

Carcinoma, Squamous Cell, Laryngeal Diseases

NCT01219673 2015-02-10

Symptom Burden in Head and Neck Cancer

Phase 1/2 Terminated

1 enrolled 2 charts

Head & Neck

cyclopia sequence, Carcinoma, Head and Neck Neoplasms, Laryngeal Diseases

NCT00589667 2014-04-02

A Phase II Study of Pemetrexed Plus Gemcitabine for Metastatic/Recurrent Head and Neck Cancer (HNSCC)

Phase 2 Completed

26 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Head and Neck Neoplasms, Laryngeal Diseases

NCT01208883 2014-01-24

A Feasibility Study On Continuous Adaptive [18f]Fdg-Pet-Guided Radiotherapy For Head and Neck Cancer

Phase 1 Completed

10 enrolled

Head & Neck

Carcinoma, Squamous Cell, Laryngeal Diseases

NCT01427205 2013-04-05

Phase II Study of Cetuximab With or Without OSI-906 in Head and Neck Squamous Cell Carcinoma (HNSCC)

Phase 2 Withdrawn

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Laryngeal Diseases, Neoplasm Metastasis, Recurrence

NCT00396617 2012-07-02

Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy

Phase 1 Unknown

14 enrolled

Head & Neck

Carcinoma, Laryngeal Diseases, Laryngeal Neoplasms, Pharyngeal Neoplasms