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Leiomyoma

NCT03194646 2025-07-28

ASTEROID 6

Phase 3 Terminated

1,272 enrolled 16 charts

Leiomyoma

NCT03271489 2025-07-22

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

478 enrolled 9 charts

Leiomyoma, Menorrhagia

NCT03751124 2024-06-25

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

229 enrolled 66 charts

Leiomyoma, Menorrhagia, Myofibroma

NCT03412890 2024-05-09

LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

477 enrolled 27 charts

Leiomyoma, Menorrhagia

NCT00133705 2023-09-25

Trial of Mifepristone for Fibroids

Phase 3 Completed

70 enrolled 6 charts

Leiomyoma

NCT03400943 2023-05-03

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)

Phase 3 Terminated

93 enrolled 19 charts

Leiomyoma, Menorrhagia

NCT03400956 2022-06-30

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4)

Phase 3 Terminated

103 enrolled 18 charts

Leiomyoma, Menorrhagia

NCT03103087 2022-04-20

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

382 enrolled 57 charts

Leiomyoma, Menorrhagia

NCT03049735 2022-04-19

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

388 enrolled 54 charts

Leiomyoma, Menorrhagia

NCT02691494 2021-07-13

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

Phase 3 Completed

378 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT02925494 2021-07-13

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

433 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT02654054 2020-06-29

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

413 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT01629563 2019-09-04

PEARLIV

Phase 3 Completed

451 enrolled 14 charts

Leiomyoma

NCT02147158 2019-06-04

A Study of the Efficacy and Safety of Ulipristal Acetate Intermittent Treatment for Abnormal Uterine Bleeding Associated With Leiomyomas

Phase 3 Completed

432 enrolled 16 charts

Gynecologic

Leiomyoma, Uterine Hemorrhage

NCT02147197 2019-04-30

A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas

Phase 3 Completed

157 enrolled 11 charts

Gynecologic

Leiomyoma, Uterine Hemorrhage

NCT02655224 2019-03-22

A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

Phase 3 Completed

65 enrolled 28 charts

Leiomyoma

NCT02655237 2019-03-22

A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids

Phase 3 Completed

281 enrolled 37 charts

Leiomyoma

NCT00365989 2019-02-05

MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication

Phase 3 Completed

50 enrolled 7 charts

Leiomyoma, Neoplasms, Myofibroma

NCT00702702 2014-08-21

Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

56 enrolled 1 chart

Classical hematology

Anemia, Leiomyoma

NCT00735553 2014-08-21

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

77 enrolled 1 chart

Leiomyoma

NCT00737282 2014-08-21

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Phase 3 Terminated

175 enrolled 1 chart

Leiomyoma

NCT00785356 2014-08-21

Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

8 enrolled 1 chart

Classical hematology

Anemia, Leiomyoma

NCT00853567 2014-08-21

Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

71 enrolled 1 chart

Leiomyoma

NCT01069120 2014-08-21

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

27 enrolled 1 chart

Leiomyoma

Clinical Trials

Dex-Fib

ASTEROID 6

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Trial of Mifepristone for Fibroids

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4)

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

PEARLIV

A Study of the Efficacy and Safety of Ulipristal Acetate Intermittent Treatment for Abnormal Uterine Bleeding Associated With Leiomyomas

A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas

A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids

MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication

Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine Fibroids

Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids