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Phase 3 × INDUSTRY × Leiomyoma × Clear all

NCT04756037 2026-05-13

SERENE

Phase 3 Completed

1,164 enrolled 16 charts

Endometriosis, Leiomyoma

NCT07378098 2026-05-01

to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia

Phase 3 Recruiting

Leiomyoma, Menorrhagia

NCT06671548 2026-02-02

Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Recruiting

Leiomyoma, Menorrhagia

NCT05445167 2025-11-25

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain

Phase 3 Completed

Leiomyoma

NCT05862272 2025-08-06

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Phase 3 Recruiting

Endometriosis, Leiomyoma, Myofibroma

NCT03194646 2025-07-28

ASTEROID 6

Phase 3 Terminated

1,272 enrolled 16 charts

Leiomyoma

NCT03271489 2025-07-22

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

478 enrolled 9 charts

Leiomyoma, Menorrhagia

NCT05440383 2025-03-14

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia

Phase 3 Completed

Leiomyoma

NCT03240523 2024-10-18

ASTEROID 5

Phase 3 Terminated

Leiomyoma

NCT03751124 2024-06-25

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

229 enrolled 66 charts

Leiomyoma, Menorrhagia, Myofibroma

NCT03412890 2024-05-09

LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

477 enrolled 27 charts

Leiomyoma, Menorrhagia

NCT03400943 2023-05-03

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)

Phase 3 Terminated

93 enrolled 19 charts

Leiomyoma, Menorrhagia

NCT05620355 2023-03-21

Efficacy and Safety of BG2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids.

Phase 3 Unknown

Leiomyoma, Menorrhagia

NCT03476928 2022-07-08

ASTEROID 8

Phase 3 Terminated

Leiomyoma, Menorrhagia

NCT03400956 2022-06-30

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4)

Phase 3 Terminated

103 enrolled 18 charts

Leiomyoma, Menorrhagia

NCT03103087 2022-04-20

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

382 enrolled 57 charts

Leiomyoma, Menorrhagia

NCT03049735 2022-04-19

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

388 enrolled 54 charts

Leiomyoma, Menorrhagia

NCT02691494 2021-07-13

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

Phase 3 Completed

378 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT02925494 2021-07-13

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Phase 3 Completed

433 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT03070899 2021-06-09

PRIMROSE 1

Phase 3 Completed

Leiomyoma, Menorrhagia

NCT03070951 2021-03-05

PRIMROSE 2

Phase 3 Completed

Leiomyoma, Menorrhagia

NCT02654054 2020-06-29

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Phase 3 Completed

413 enrolled 16 charts

Leiomyoma, Menorrhagia

NCT03699176 2020-01-18

ASTEROID 7

Phase 3 Withdrawn

Leiomyoma

NCT01629563 2019-09-04

PEARLIV

Phase 3 Completed

451 enrolled 14 charts

Leiomyoma

NCT02147158 2019-06-04

A Study of the Efficacy and Safety of Ulipristal Acetate Intermittent Treatment for Abnormal Uterine Bleeding Associated With Leiomyomas

Phase 3 Completed

432 enrolled 16 charts

Leiomyoma, Uterine Hemorrhage

NCT02147197 2019-04-30

A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas

Phase 3 Completed

157 enrolled 11 charts

Leiomyoma, Uterine Hemorrhage

NCT02655224 2019-03-22

A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

Phase 3 Completed

65 enrolled 28 charts

Leiomyoma

NCT02655237 2019-03-22

A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids

Phase 3 Completed

281 enrolled 37 charts

Leiomyoma

NCT00365989 2019-02-05

MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication

Phase 3 Completed

50 enrolled 7 charts

Leiomyoma, Neoplasms, Myofibroma

NCT00295217 2018-12-20

MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation

Phase 3 Completed

Leiomyoma, Myofibroma

NCT01156857 2016-01-15

PEARLIII

Phase 3 Completed

Leiomyoma

NCT01252069 2016-01-13

PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARLIII-extension Study)

Phase 3 Completed

Leiomyoma

NCT01642472 2016-01-08

PEARLext2

Phase 3 Completed

Leiomyoma

NCT00702702 2014-08-21

Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

56 enrolled 1 chart

Classical hematology

Anemia, Leiomyoma

NCT00735553 2014-08-21

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

77 enrolled 1 chart

Leiomyoma

NCT00737282 2014-08-21

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Phase 3 Terminated

175 enrolled 1 chart

Leiomyoma

NCT00785356 2014-08-21

Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

8 enrolled 1 chart

Classical hematology

Anemia, Leiomyoma

NCT00853567 2014-08-21

Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

71 enrolled 1 chart

Leiomyoma

NCT01069120 2014-08-21

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids

Phase 3 Terminated

27 enrolled 1 chart

Leiomyoma

NCT00874302 2014-06-27

Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms

Phase 3 Withdrawn

Leiomyoma

NCT01553123 2013-02-07

Efficacy and Safety Study of Ulipristal Acetate in Females With Anemia Associated With Uterine Leiomyoma

Phase 3 Withdrawn

Leiomyoma

NCT01064960 2012-12-04

Therapeutic MRI-HIFU Ablation of Uterine Fibroids in a 3T MRI Scanner

Phase 3 Completed

Connective Tissue Diseases, Leiomyoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Connective Tissue, Neoplasms, Muscle Tissue, Neoplasms, Connective and Soft Tissue, Myofibroma

NCT01141062 2012-12-04

HIFU

Phase 3 Completed

Leiomyoma, Myofibroma

NCT00152256 2008-05-29

A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00152269 2008-05-29

Treatment of Uterine Fibroids With Asoprisnil(J867)

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00156195 2008-05-29

Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00156208 2008-05-29

Safety of Treatment of Uterine Fibroids With Asoprisnil

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00160381 2008-05-29

A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage

NCT00156156 2008-05-28

Study of Asoprisnil in the Treatment of Uterine Fibroids.

Phase 3 Completed

Leiomyoma, Menorrhagia, Metrorrhagia, Uterine Hemorrhage