NCT07070232 2026-03-12A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsBioNTech SEPhase 1/2 Recruiting980 enrolled
NCT07111520 2025-10-22A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)BioNTech SEPhase 1/2 Recruiting420 enrolled
NCT05057013 2025-08-11A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid TumoursCancer Research UKPhase 1/2 Active not recruiting81 enrolled
NCT02912949 2025-04-29A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)Partner Therapeutics, Inc.Phase 2 Active not recruiting250 enrolled 3 FDA
NCT03321981 2024-03-07MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.Merus B.V.Phase 2 Completed105 enrolled 23 charts
NCT00734305 2016-09-01Phase I Safety Study of the Drug MM-121 in Patients With Advanced Solid Tumors Resisting Ordinary TreatmentMerrimack PharmaceuticalsPhase 1 Completed44 enrolled 12 charts
NCT00994123 2016-08-22A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung CancerMerrimack PharmaceuticalsPhase 1/2 Completed162 enrolled 11 charts
NCT00730470 2010-07-29Phase I Study of U3P1287/01, Including Patients With Advanced Solid TumorsU3 Pharma GmbHPhase 1 Completed60 enrolled