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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1

Conditions

Prostatic Neoplasms 9Breast Neoplasms 7Neoplasms 4Lymphoma 4Brain Neoplasms 4Lymphoma, Non-Hodgkin 3Urinary Bladder Neoplasms 2Triple Negative Breast Neoplasms 2Stomach Neoplasms 2Lymphoma, B-Cell 2Liver Neoplasms 2Leukemia 2Head and Neck Neoplasms 2Colonic Neoplasms 2Carcinoma, Hepatocellular 2Carcinoma in Situ 2Burkitt Lymphoma 2Vulvar Neoplasms 1Vulvar Diseases 1Vasculitis 1Uterine Cervical Neoplasms 1Uterine Cervical Dysplasia 1Squamous Cell Carcinoma of Head and Neck 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Philadelphia Chromosome 1Papillomavirus Infections 1Pancreatic Neoplasms 1Osteomyelitis 1Neurofibromatosis 1 1

Interventions

ofatumumab 10Cyclophosphamide 6fludarabine 5ibrutinib 4fludarabine phosphate 4Bortezomib 3Tablets 2Chlorambucil 2tirabrutinib 1pegaspargase 1nelarabine 1immunotoxin HA22 1bempegaldesleukin 1Whole-Body Irradiation 1Vincristine 1Panobinostat 1Observation 1Nivolumab 1Mitoxantrone 1Methotrexate 1Mesna 1Mercaptopurine 1Magnetic Resonance Imaging 1MLN 8237 1Lenalidomide 1KW-2478 1Hsp90 inhibitor KU757 1Etoposide 1Electrocardiography 1Echocardiography 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Leukemia, B-Cell × Magnetic Resonance Imaging × Clear all
NCT03448393 2025-06-04

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
54 enrolled 24 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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