Announcements Trials
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Phase

Phase 1 2Phase 3 1

Status

Completed 38Terminated 10Active not recruiting 3

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 2Lymphoid 2

Conditions

Breast Neoplasms 116Carcinoma, Non-Small-Cell Lung 67Multiple Myeloma 56Prostatic Neoplasms 55Lymphoma 40Neoplasm Metastasis 38Leukemia, Lymphocytic, Chronic, B-Cell 35Melanoma 32Leukemia, Myeloid, Acute 32Neoplasms 31Ovarian Neoplasms 30Lymphoma, Non-Hodgkin 27Lung Neoplasms 26Hematologic Neoplasms 25Triple Negative Breast Neoplasms 24Glioblastoma 22Myelodysplastic Syndromes 20Fallopian Tube Neoplasms 20Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Hodgkin Disease 19Sarcoma 18Carcinoma, Renal Cell 18Squamous Cell Carcinoma of Head and Neck 16Small Cell Lung Carcinoma 16Glioma 16Urinary Bladder Neoplasms 15Colorectal Neoplasms 15Lymphoma, Mantle-Cell 14Leukemia 14Head and Neck Neoplasms 14

Interventions

uproleselan 1fludarabine 1blinatumomab 1Standard of Care 1Specimen Handling 1Nivolumab 1N,N-dicyclohexyl-isoborneol-10-sulfonamide 1Leucovorin 1Ipilimumab 1Cytarabine 1CTLA-4 Antigen 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Active not recruiting × Has results × Leukemia, Biphenotypic, Acute × Clear all
NCT05146739 2026-06-02

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

National Cancer Institute (NCI)

Phase 1 Active not recruiting
8 enrolled 15 charts
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT02879695 2026-05-29

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

Phase 1 Active not recruiting
28 enrolled 16 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Biphenotypic, Acute

NCT05316701 2026-03-04

Orca-T

Orca Biosystems, Inc.

Phase 3 Active not recruiting
187 enrolled 15 charts
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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