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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1Classical hematology 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Blast Crisis 4Pancreatic Neoplasms 3Leukemia, Myelomonocytic, Chronic 3Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 3Leukemia, Myeloid, Acute 3Leukemia, Myeloid, Accelerated Phase 3Leukemia, Lymphocytic, Chronic, B-Cell 3Congenital Abnormalities 3Carcinoma, Non-Small-Cell Lung 3Vaginal Neoplasms 2Uterine Cervical Neoplasms 2Myeloproliferative Disorders 2Myelodysplastic-Myeloproliferative Diseases 2Myelodysplastic Syndromes 2Lung Neoplasms 2Leukemia 2Carcinoma, Ovarian Epithelial 2Anemia, Refractory, with Excess of Blasts 2Waldenstrom Macroglobulinemia 1Vulvar Neoplasms 1Thrombocythemia, Essential 1Sezary Syndrome 1Prostatic Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Pdgfra-Associated Chronic Eosinophilic Leukemia 1Pancreatic Adenocarcinoma 1

Interventions

Cytarabine 56Etoposide 24Daunorubicin 22Filgrastim 18Busulfan 16fludarabine phosphate 14Mitoxantrone 14Idarubicin 14Cyclophosphamide 14Peripheral Blood Stem Cell Transplantation 12tipifarnib 11Gemtuzumab 11Flow Cytometry 9Cyclosporine 9Antilymphocyte Serum 9sargramostim 8Methotrexate 8Clofarabine 8Gene Expression Profiling 7Topotecan 6Radiotherapy 6Azacitidine 6valspodar 5alvocidib 5aldesleukin 5Melphalan 5Whole-Body Irradiation 4Observation 4Methylprednisolone 4Granulocyte Colony-Stimulating Factor 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Leukemia, Erythroblastic, Acute × 3-aminopyridine-2-carboxaldehyde thiosemicarbazone × Clear all
NCT00077558 2010-03-10

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic Syndrome

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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