Announcements Trials
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Phase

Phase 2 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell 43Lymphoma, Follicular 23Lymphoma, Non-Hodgkin 17Lymphoma, Mantle-Cell 16Lymphoma, Large B-Cell, Diffuse 15Lymphoma 14Lymphoma, B-Cell, Marginal Zone 12Lymphoma, B-Cell 8Recurrence 7Neoplasms 6Burkitt Lymphoma 5Neoplasm, Residual 3Leukemia, B-Cell 3Leukemia, Hairy Cell 2Leukemia 2Dendritic Cell Sarcoma, Interdigitating 2Waldenstrom Macroglobulinemia 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Prostatic Neoplasms 1Part1: Advanced B-cell Malignancies 1Ovarian Neoplasms 1Mesothelioma 1Melanoma 1Mature B-cell Malignancies 1Mature B-Cell Malignancies 1Lymphoproliferative Disorders 1Lymphatic Diseases 1Leukemia, Prolymphocytic 1

Interventions

Rituximab 7Vemurafenib 4Cyclophosphamide 4Cladribine 4Specimen Handling 3Biopsy 3obinutuzumab 2ibrutinib 2fludarabine phosphate 2fludarabine 2binimetinib 2Diphenhydramine 2Dexamethasone 2Calcium Dobesilate 2CT-P10 2Acetaminophen 2venetoclax 1tovorafenib 1polatuzumab vedotin 1pembrolizumab 1immunotoxin HA22 1encorafenib 1dexamethasone acetate 1dexamethasone 21-phosphate 1brexucabtagene autoleucel 1auricularum 1acalabrutinib 1Whole-Body Irradiation 1Valganciclovir 1Transplantation 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Leukemia, Hairy Cell × obinutuzumab × 1 year × Clear all
NCT06561360 2026-05-26

A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

Memorial Sloan Kettering Cancer Center

Phase 2 Recruiting
86 enrolled
Other hematologic neoplasm

Leukemia, Hairy Cell

NCT03410875 2026-02-12

A Phase II Study of the BRAF Inhibitor, Vemurafenib, Plus Obinutuzumab in Patients With Previously Untreated Classical Hairy Cell Leukemia

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
30 enrolled
Other hematologic neoplasm

Leukemia, Leukemia, Hairy Cell

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