Announcements Trials
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Phase

Phase 2 2

Status

Recruiting 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2

Conditions

Ovarian Neoplasms 3Pancreatic Neoplasms 2Neoplasm Metastasis 2Multiple Myeloma 2Lymphoma 2Leukemia, Hairy Cell 2Hematologic Neoplasms 2Endometrial Neoplasms 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Thyroid Neoplasms 1Stomach Neoplasms 1Rectal Neoplasms 1Prostatic Neoplasms 1Melanoma 1Lung Neoplasms 1Klatskin Tumor 1Glioma 1Gallbladder Neoplasms 1Fallopian Tube Neoplasms 1Esophageal Neoplasms 1Colorectal Neoplasms 1Colonic Neoplasms 1Cholangiocarcinoma 1Carcinoma, Renal Cell 1Carcinoma, Hepatocellular 1Breast Neoplasms 1Anatomic Stage IV Breast Cancer AJCC v8 1

Interventions

Rituximab 6fludarabine phosphate 3Vorinostat 3Specimen Handling 3Biopsy 3sargramostim 2ibrutinib 2binimetinib 2Sunitinib 2RFB4(dsFv)-PE38 recombinant immunotoxin 2Polymerase Chain Reaction 2Peripheral Blood Stem Cell Transplantation 2MK 2206 2Interferon-alpha 2Ifosfamide 2Flow Cytometry 2Etoposide 2Diphenhydramine 2Cladribine 2Carboplatin 2Bendamustine Hydrochloride 2B3(Fv)-PE38KDEL recombinant immunotoxin 2Analgesia 2Acetaminophen 2venetoclax 1veliparib 1tovorafenib 1tanespimycin 1obatoclax 1merphos 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Leukemia, Hairy Cell × binimetinib × Clear all
NCT04322383 2026-03-31

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

National Institutes of Health Clinical Center (CC)

Phase 2 Recruiting
40 enrolled
Other hematologic neoplasm

Leukemia, Hairy Cell

NCT04324112 2026-03-31

Encorafenib Plus Binimetinib for People With BRAF V600 Mutated Relapsed/Refractory HCL

National Institutes of Health Clinical Center (CC)

Phase 2 Recruiting
45 enrolled
Other hematologic neoplasm

Leukemia, Hairy Cell

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