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Phase

Phase 2 4Phase EARLY_PHASE1 1Phase 4 1Phase 3 1

Status

Recruiting 2Completed 1Active not recruiting 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 4Lymphoid 4

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell 4Multiple Myeloma 2Breast Neoplasms 2Urinary Bladder Neoplasms 1Prostatic Neoplasms 1Pneumonia, Pneumococcal 1Neoplasms, Plasma Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lung Neoplasms 1Leukemia 1Colorectal Neoplasms 1Colonic Neoplasms 1

Interventions

Cyclophosphamide 146Rituximab 138fludarabine phosphate 111Mycophenolic Acid 69Peripheral Blood Stem Cell Transplantation 63fludarabine 59Tacrolimus 58Whole-Body Irradiation 51venetoclax 46Busulfan 46ibrutinib 45Cyclosporine 42Lenalidomide 41Filgrastim 41Alemtuzumab 41Melphalan 40Radiotherapy 39obinutuzumab 37Antilymphocyte Serum 35Etoposide 33Methotrexate 32ofatumumab 29acalabrutinib 26Bendamustine Hydrochloride 24sargramostim 22Methylprednisolone 18Cytarabine 18zanubrutinib 17Pentostatin 17Granulocyte Colony-Stimulating Factor 16

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Lymphocytic, Chronic, B-Cell × Pneumococcal Vaccines × Clear all
NCT01351896 2026-05-27

Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
49 enrolled 34 charts
LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT05183854 2026-04-09

Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial

University of Utah

Phase 2 Recruiting
61 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT05417165 2026-01-07

Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia

Ohio State University Comprehensive Cancer Center

Phase 2 Recruiting
80 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT00323557 2012-12-05

Immuno-Augmentation With GM-CSF of Pneumococcal Vaccine in Chronic Lymphocytic Leukemia Patients

M.D. Anderson Cancer Center

Phase 2 Completed
39 enrolled 4 charts
LymphoidOther hematologic neoplasm

Leukemia, Pneumonia, Pneumococcal, Leukemia, Lymphocytic, Chronic, B-Cell

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