Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 4Neoplasm Metastasis 2Mastocytosis, Systemic 2Sarcoma 1Recurrence 1Melanoma 1Lung Neoplasms 1Leukemia, Mast-Cell 1Core Binding Factor Acute Myeloid Leukemia 1Colorectal Neoplasms 1

Interventions

fludarabine phosphate 3midostaurin 2Whole-Body Irradiation 2Therapeutics 2Mycophenolic Acid 2Methotrexate 2Cyclosporine 2Busulfan 2thymoglobulin 1ibrutinib 1hydrocortisone valerate 1fludarabine 1denileukin diftitox 1avapritinib 1Thiotepa 1Tacrolimus 1Sunitinib 1Rituximab 1Peripheral Blood Stem Cell Transplantation 1Methylprednisolone Hemisuccinate 1Methylprednisolone Acetate 1Methylprednisolone 1Leucovorin 1Imatinib Mesylate 1Hydrocortisone 1Granulocyte Colony-Stimulating Factor 1Granisetron 1Filgrastim 1Epoetin Alfa 1Enzyme-Linked Immunosorbent Assay 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Mast-Cell × avapritinib × Clear all
NCT03580655 2026-04-24

(PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis

Blueprint Medicines Corporation

Phase 2 Completed
107 enrolled 30 charts 1 FDA
LymphoidMyeloidOther hematologic neoplasm

Leukemia, Mast-Cell, Mastocytosis, Systemic

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