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Phase

Phase EARLY_PHASE1 1Phase 2 1

Status

Completed 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 21Leukemia, Myeloid, Acute 20Lymphoma, Non-Hodgkin 19Hodgkin Disease 18Multiple Myeloma 17Myelodysplastic Syndromes 16Lymphoma 16Graft vs Host Disease 16Lymphoma, Mantle-Cell 15Leukemia, Lymphocytic, Chronic, B-Cell 15Leukemia 14Sarcoma 11Lymphoma, Large B-Cell, Diffuse 11Lymphoma, Follicular 11Glioblastoma 11Tuberous Sclerosis 10Lymphoma, B-Cell, Marginal Zone 10Carcinoma, Renal Cell 10Neoplasms 9Hematologic Neoplasms 9Gliosarcoma 9Carcinoma, Hepatocellular 9Breast Neoplasms 9Brain Neoplasms 9Waldenstrom Macroglobulinemia 8Myeloproliferative Disorders 8Melanoma 8Burkitt Lymphoma 8Recurrence 7Neoplasm Metastasis 7

Interventions

Cytarabine 54Etoposide 22Daunorubicin 20Filgrastim 18Busulfan 15Idarubicin 14Cyclophosphamide 14fludarabine phosphate 13Peripheral Blood Stem Cell Transplantation 12Mitoxantrone 12tipifarnib 11Gemtuzumab 10Flow Cytometry 10Antilymphocyte Serum 10Cyclosporine 9sargramostim 8Gene Expression Profiling 8Clofarabine 8Radiotherapy 7Methotrexate 7Topotecan 6valspodar 5aldesleukin 5Azacitidine 5alvocidib 4Observation 4Methylprednisolone 4Melphalan 4Granulocyte Colony-Stimulating Factor 4Arsenic Trioxide 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Leukemia, Megakaryoblastic, Acute × Sirolimus × Clear all
NCT01822015 2025-04-29

Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Thomas Jefferson University

Phase EARLY_PHASE1 Completed
55 enrolled
Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00634244 2015-07-07

Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

National Cancer Institute (NCI)

Phase 2 Completed
92 enrolled 10 charts
Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

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