Announcements Trials
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Phase

Phase 1 2

Status

Suspended 1Recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Plasma cell 2Other hematologic neoplasm 2Myeloid 2Lymphoid 2Gastrointestinal 1

Conditions

Melanoma 16Neoplasm Metastasis 11Ovarian Neoplasms 9Pancreatic Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Stomach Neoplasms 6Skin Neoplasms 6Leukemia, Myeloid, Acute 6Colorectal Neoplasms 6Carcinoma, Renal Cell 6Triple Negative Breast Neoplasms 4Gastrointestinal Neoplasms 4Breast Neoplasms 4Vulvar Neoplasms 3Uterine Cervical Neoplasms 3Urogenital Neoplasms 3Rectal Neoplasms 3Neuroblastoma 3Myelodysplastic Syndromes 3Multiple Myeloma 3Leukemia 3Colonic Neoplasms 3Vaginal Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pleural Effusion, Malignant 2Penile Neoplasms 2Oropharyngeal Neoplasms 2Neoplasms 2

Interventions

Cyclophosphamide 29fludarabine phosphate 22Whole-Body Irradiation 20Mycophenolic Acid 20fludarabine 19asciminib 19nilotinib 16Tacrolimus 13Imatinib Mesylate 13Melphalan 11Dasatinib 9Sirolimus 8Peripheral Blood Stem Cell Transplantation 8Thiotepa 7Granulocyte Colony-Stimulating Factor 7Busulfan 7bosutinib 6Mesna 6Cyclosporine 6ponatinib 5Stem Cell Transplantation 5Filgrastim 5venetoclax 4ruxolitinib 4blinatumomab 4Specimen Handling 4Cyclosporins 4thymoglobulin 3Bone Marrow Transplantation 3Antilymphocyte Serum 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Leukemia, Myelogenous, Chronic, BCR-ABL Positive × aldesleukin × 1 year × Clear all
NCT06904066 2026-06-04

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
86 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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