Announcements Trials
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Phase

Phase 1 1

Status

Recruiting 52Completed 35Active not recruiting 31Terminated 11Not yet recruiting 10Suspended 1Enrolling by invitation 1Available 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Gastrointestinal 1

Conditions

Neoplasms 18Breast Neoplasms 16Leukemia, Myeloid, Acute 15Glioblastoma 13Colorectal Neoplasms 13Prostatic Neoplasms 12Neoplasm Metastasis 10Carcinoma, Non-Small-Cell Lung 10Pancreatic Neoplasms 9Lung Neoplasms 9Glioma 8Carcinoma, Hepatocellular 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Multiple Myeloma 7Head and Neck Neoplasms 7Carcinoma, Renal Cell 7Ovarian Neoplasms 6Myelodysplastic Syndromes 6Hematologic Neoplasms 6Triple Negative Breast Neoplasms 5Rectal Neoplasms 5Melanoma 5Uterine Cervical Neoplasms 4Sarcoma 4Colonic Neoplasms 4Brain Neoplasms 4Solid Tumor 3Small Cell Lung Carcinoma 3Recurrence 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Interleukin-2 1IL32 protein, human 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × 1 year × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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