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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Dermatologic 1

Conditions

Multiple Myeloma 7Recurrence 5Leukemia, Myeloid, Acute 5Glioblastoma 4Colorectal Neoplasms 3Neoplasms, Plasma Cell 2Melanoma 2Lymphoma, T-Cell, Peripheral 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Lymphocytic, Chronic, B-Cell 2Glioma 2Carcinoma, Squamous Cell 2Brain Neoplasms 2Astrocytoma 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Thymoma 1Small Cell Lung Carcinoma 1Sarcoma 1Richter's Transformation 1Prostatic Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Oligodendroglioma 1Neoplasm Metastasis 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1

Interventions

Cyclophosphamide 48fludarabine phosphate 45fludarabine 38Whole-Body Irradiation 38Mycophenolic Acid 37Imatinib Mesylate 36nilotinib 34Tacrolimus 30Busulfan 23Cyclosporine 18Melphalan 17Granulocyte Colony-Stimulating Factor 17Dasatinib 17thymoglobulin 16Methotrexate 16Thiotepa 15Peripheral Blood Stem Cell Transplantation 15Antilymphocyte Serum 15bosutinib 13Filgrastim 13Stem Cell Transplantation 11sargramostim 8ponatinib 8Cytarabine 8Cyclosporins 8Cord Blood Stem Cell Transplantation 8Clofarabine 8Sirolimus 7Rituximab 7plerixafor 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × selinexor × Clear all
NCT01607892 2023-01-26

Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer

Karyopharm Therapeutics Inc

Phase 1 Completed
286 enrolled 26 charts
DermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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