Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 3OTHER 2NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2

Conditions

Leukemia, Myeloid, Acute 132Myelodysplastic Syndromes 57Leukemia 32Leukemia, Myelomonocytic, Chronic 23Recurrence 18Lymphoma, Large B-Cell, Diffuse 10Myeloproliferative Disorders 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Neoplasms 8Congenital Abnormalities 7Primary Myelofibrosis 6Melanoma 6Hodgkin Disease 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Ovarian Neoplasms 5Blast Crisis 5Thrombocythemia, Essential 4Polycythemia Vera 4Myelodysplastic-Myeloproliferative Diseases 4Lymphoma 4Leukemia, Monocytic, Acute 4Leukemia, Biphenotypic, Acute 4Anemia, Refractory, with Excess of Blasts 4Neoplasm Metastasis 3Leukemia, Myelomonocytic, Acute 3Leukemia, Myeloid, Accelerated Phase 3Head and Neck Neoplasms 3Fallopian Tube Neoplasms 3Breast Neoplasms 3Triple Negative Breast Neoplasms 2

Interventions

Cyclophosphamide 82Imatinib Mesylate 81fludarabine phosphate 67fludarabine 62Whole-Body Irradiation 55Mycophenolic Acid 54Tacrolimus 42nilotinib 40Busulfan 39Dasatinib 32Cyclosporine 30Peripheral Blood Stem Cell Transplantation 28thymoglobulin 25Melphalan 25Thiotepa 24Cytarabine 24Granulocyte Colony-Stimulating Factor 23Antilymphocyte Serum 23Methotrexate 21Filgrastim 21Stem Cell Transplantation 20ponatinib 16Sirolimus 16sargramostim 14Cord Blood Stem Cell Transplantation 13Rituximab 11Cyclosporins 11Clofarabine 11venetoclax 10peginterferon alfa-2b 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × Decitabine × Clear all
NCT04188405 2026-05-22

Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia Chromosome-Positive Acute Myeloid Leukemia or Myeloid Blast Phase or Accelerated Phase Chronic Myelogenous Leukemia

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
20 enrolled
MyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute

NCT01498445 2020-10-22

An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357)

M.D. Anderson Cancer Center

Phase 1/2 Terminated
32 enrolled 16 charts
MyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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