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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Multiple Myeloma 5Breast Neoplasms 4Vomiting 3Neoplasms 3Lymphoma, Non-Hodgkin 3Stomach Neoplasms 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Neoplasm Metastasis 2Nausea 2Hodgkin Disease 2Hematologic Neoplasms 2Endometrial Neoplasms 2Burkitt Lymphoma 2Uterine Cervical Neoplasms 1Stomatitis 1Squamous Cell Carcinoma of Head and Neck 1Renal Insufficiency 1Rectal Neoplasms 1Prostatic Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Postoperative Nausea and Vomiting 1Pathologic Complete Response 1Paraproteinemias 1Pain 1Ovarian Neoplasms 1Neoplasms, Plasma Cell 1Neoplasms by Histologic Type 1NSCLC 1Mucositis 1Mastocytosis, Systemic 1

Interventions

Cyclophosphamide 82Imatinib Mesylate 81fludarabine phosphate 67fludarabine 62Whole-Body Irradiation 55Mycophenolic Acid 54Tacrolimus 42nilotinib 40Busulfan 39Dasatinib 32Cyclosporine 30Peripheral Blood Stem Cell Transplantation 28thymoglobulin 25Melphalan 25Thiotepa 24Cytarabine 24Granulocyte Colony-Stimulating Factor 23Antilymphocyte Serum 23Methotrexate 21Filgrastim 21Stem Cell Transplantation 20ponatinib 16Sirolimus 16sargramostim 14Cord Blood Stem Cell Transplantation 13Rituximab 11Cyclosporins 11Clofarabine 11venetoclax 10peginterferon alfa-2b 10

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × Diphenhydramine × Clear all
NCT04681105 2026-01-28

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

City of Hope Medical Center

Phase 1 Completed
13 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Mastocytosis, Systemic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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