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Phase

Phase 2 2Phase EARLY_PHASE1 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Sarcoma 1

Conditions

Leukemia, Myeloid, Acute 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma, Non-Hodgkin 9Congenital Abnormalities 9Myelodysplastic Syndromes 7Multiple Myeloma 7Lymphoma, Mantle-Cell 7Leukemia, Lymphocytic, Chronic, B-Cell 7Lymphoma, Large B-Cell, Diffuse 6Leukemia 6Hodgkin Disease 6Myeloproliferative Disorders 5Leukemia, Myeloid, Accelerated Phase 5Waldenstrom Macroglobulinemia 4Sezary Syndrome 4Recurrence 4Mycosis Fungoides 4Lymphoma, T-Cell, Cutaneous 4Lymphoma, Follicular 4Lymphoma, Extranodal NK-T-Cell 4Lymphoma, B-Cell, Marginal Zone 4Lymphoma 4Graft vs Host Disease 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, T-Cell, Peripheral 3Lymphoma, Large-Cell, Immunoblastic 3Lymphoma, Large-Cell, Anaplastic 3Leukemia, Myelomonocytic, Juvenile 3Intraocular Lymphoma 3Immunoblastic Lymphadenopathy 3

Interventions

Imatinib Mesylate 60Cyclophosphamide 57fludarabine phosphate 51fludarabine 43Whole-Body Irradiation 41Mycophenolic Acid 41Tacrolimus 33nilotinib 31Dasatinib 31Busulfan 29Peripheral Blood Stem Cell Transplantation 23Cyclosporine 22Melphalan 21Thiotepa 20Granulocyte Colony-Stimulating Factor 19Filgrastim 18thymoglobulin 17Cytarabine 17Antilymphocyte Serum 15Stem Cell Transplantation 14sargramostim 13Methotrexate 13ponatinib 12asciminib 10Cyclosporins 10Cord Blood Stem Cell Transplantation 10bosutinib 9Rituximab 9Interferon-alpha 9Clofarabine 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × Transplantation × Clear all
NCT02790515 2025-08-12

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
170 enrolled
LymphoidMyeloidOther hematologic neoplasmSarcoma

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Sarcoma, Myeloid, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT00003838 2023-09-21

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
202 enrolled 17 charts
LymphoidMyeloidOther hematologic neoplasm

Graft vs Host Disease, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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