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Phase

Phase 1 1

Status

Completed 4Terminated 1Suspended 1Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Melanoma 7Neoplasm Metastasis 5Carcinoma, Non-Small-Cell Lung 5Stomach Neoplasms 4Ovarian Neoplasms 4Breast Neoplasms 4Uterine Cervical Neoplasms 3Skin Neoplasms 3Pancreatic Neoplasms 3Multiple Myeloma 3Lung Neoplasms 3Leukemia, Myeloid, Acute 3Carcinoma, Renal Cell 3Vulvar Neoplasms 2Vaginal Neoplasms 2Urogenital Neoplasms 2Triple Negative Breast Neoplasms 2Pleural Effusion, Malignant 2Penile Neoplasms 2Oropharyngeal Neoplasms 2Neuroblastoma 2Myelodysplastic Syndromes 2Mesothelioma, Malignant 2Leukemia, Myeloid 2Leukemia 2Hematologic Neoplasms 2Carcinoma, Merkel Cell 2Anus Neoplasms 2Uveal Melanoma 1Urinary Bladder Neoplasms 1

Interventions

asciminib 10Cyclophosphamide 9Mycophenolic Acid 7fludarabine 5Whole-Body Irradiation 5nilotinib 4fludarabine phosphate 4Stem Cell Transplantation 4Specimen Handling 4Dasatinib 4olverembatinib 3bosutinib 3Imatinib Mesylate 3Cyclosporine 3venetoclax 2ponatinib 2blinatumomab 2X-Rays 2Thiotepa 2Tacrolimus 2Sirolimus 2Melphalan 2Magnetic Resonance Spectroscopy 2Hematopoietic Stem Cell Transplantation 2Granulocyte Colony-Stimulating Factor 2Filgrastim 2Cyclosporins 2Bone Marrow Transplantation 2Blood Component Removal 2Biopsy 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Leukemia, Myelogenous, Chronic, BCR-ABL Positive × aldesleukin × Clear all
NCT06904066 2026-06-04

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
86 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

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