Clinical Trials

80 enrolled

Leukemia, Myeloid, Acute

NCT02668653 2024-08-06

QuANTUM-First

539 enrolled 20 charts 1 FDA

Leukemia, Leukemia, Myeloid, Acute

NCT03379727 2024-02-29

Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.

301 enrolled 9 charts

Leukemia, Myeloid, Acute

NCT02013648 2024-02-23

Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™)

204 enrolled

Leukemia, Myeloid, Acute

NCT03298984 2023-11-15

Ph I Study of Alvocidib and Cytarabine/Daunorubicin (7+3) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML).

32 enrolled 15 charts

Leukemia, Myeloid, Acute

NCT00046930 2023-07-05

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Classical hematologyMyeloidOther hematologic neoplasm

449 enrolled 9 charts

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT04562792 2023-06-28

Low Dose Daunorubicin in Pediatric Relapsed/Refractory Acute Leukemia

LymphoidOther hematologic neoplasm

1 enrolled 7 charts

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00005962 2023-06-22

Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia

Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute

NCT00049517 2023-06-15

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With AML Leukemia

657 enrolled 8 charts

Leukemia, Leukemia, Myeloid, Acute

NCT03416179 2023-04-21

BRIGHT AML1019

730 enrolled 35 charts

Leukemia, Myeloid, Acute

NCT01238211 2023-03-01

Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

61 enrolled 14 charts

Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT02403310 2022-10-03

A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML

21 enrolled

Chromosome Aberrations, Leukemia, Leukemia, Myeloid, Acute

NCT02582359 2022-08-24

MLN 9708 in Induction and Consolidation for Adults With AML >= 60 Years of Age

39 enrolled

Leukemia, Myeloid, Acute

NCT03563560 2022-04-12

AML

10 enrolled

Leukemia, Myeloid, Acute

NCT02914977 2022-01-14

Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia

LymphoidOther hematologic neoplasm

18 enrolled

Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00703820 2021-08-10

Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia

324 enrolled 13 charts

Leukemia, Myeloid, Acute

NCT00372593 2021-03-24

Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia

1,070 enrolled 18 charts 1 FDA

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00093600 2020-12-19

PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

69 enrolled

Congenital Abnormalities, Leukemia, Myeloid, Acute

NCT02029950 2020-10-14

Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

MyeloidOther hematologic neoplasm

50 enrolled

Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT01696084 2020-08-10

301

309 enrolled 14 charts 1 FDA

Leukemia, Myeloid, Acute

NCT01477606 2020-06-04

Protocol in Acute Myeloid Leukemia With FLT3-ITD

451 enrolled

Leukemia, Myeloid, Acute

NCT02560025 2020-05-05

Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AML

42 enrolled 12 charts

Leukemia, Myeloid, Acute

NCT01546038 2020-03-03

A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

255 enrolled 82 charts 1 FDA

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01890746 2019-09-11

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Classical hematologyOther hematologic neoplasm

148 enrolled 42 charts

Leukemia, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT01463046 2019-04-22

Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

29 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT00416598 2019-02-19

Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemia

546 enrolled 5 charts

Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT01390337 2019-02-12

A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML)

19 enrolled

Leukemia, Myeloid, Acute

NCT02323607 2019-01-25

Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations

13 enrolled

Leukemia, Myeloid, Acute

NCT01802333 2018-12-19

Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia

754 enrolled 20 charts

Leukemia, Myeloid, Acute

NCT02326584 2018-05-09

A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AML

116 enrolled

Leukemia, Myeloid, Acute

NCT01999413 2018-04-27

FAMYLY

30 enrolled

Leukemia, Myeloid, Acute

NCT00788892 2018-01-12

Trial of CPX-351 in Newly Diagnosed Elderly AML Patients

126 enrolled 12 charts

Disease, Leukemia, Leukemia, Myeloid, Acute

NCT01382147 2017-12-06

AMLCG 2008

396 enrolled

Leukemia, Myeloid, Acute

NCT01349972 2017-07-31

Alvocidib, Cytarabine, and Mitoxantrone Hydrochloride or Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

172 enrolled 12 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT01773408 2017-01-25

A Study of RO5503781 as a Single Agent or in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia

122 enrolled

Leukemia, Myeloid, Acute

NCT02084563 2016-11-08

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms

Classical hematologyMyeloidOther hematologic neoplasm

455 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Primary Myelofibrosis

NCT00121303 2016-09-20

Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

Classical hematologyMyeloidOther hematologic neoplasm

600 enrolled

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00850382 2016-03-01

Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML)

Phase 1/2 Completed

89 enrolled

Leukemia, Myeloid, Acute

NCT00085709 2015-09-30

S0106 Cytarabine and Daunorubicin w/ or w/o Gemtuzumab Followed By HD Cytarabine and Either Gemtuzumab or Nothing in de Novo AML

637 enrolled 7 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00101153 2015-07-23

Tipifarnib, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia

24 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00004217 2015-03-06

S9918 PSC 833, Daunorubicin, and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

55 enrolled

Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00023777 2015-03-06

S0112 Cytarabine and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia

71 enrolled