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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Completed 20Terminated 5Unknown 4Active not recruiting 4Recruiting 3Not yet recruiting 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 4Myeloid 1Lymphoid 1

Conditions

Carcinoma, Hepatocellular 6Leukemia, Myeloid, Acute 4Thyroid Neoplasms 2Neoplasms 2Hepatoblastoma 2Thyroid cancer, Hurthle cell 1Thyroid Diseases 1Squamous Cell Carcinoma of Head and Neck 1Rhabdomyosarcoma 1Recurrence 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Neoplasm Metastasis 1Myelodysplastic Syndromes 1Melanoma 1Gastrointestinal Stromal Tumors 1Fibrolamellar hepatocellular carcinoma 1Desmoplastic Small Round Cell Tumor 1Carcinoma 1

Interventions

Azacitidine 38Cytarabine 37venetoclax 34fludarabine 28Cyclophosphamide 21Daunorubicin 18fludarabine phosphate 17Decitabine 16Specimen Handling 15Tacrolimus 14Busulfan 13Injections 12Biopsy 12Melphalan 11Granulocyte Colony-Stimulating Factor 11CPX-351 11Mycophenolic Acid 10Idarubicin 10Stem Cell Transplantation 9Whole-Body Irradiation 8Etoposide 8decitabine and cedazuridine drug combination 7Thiotepa 7Mitoxantrone 7enasidenib 6Peripheral Blood Stem Cell Transplantation 6Methotrexate 6ivosidenib 5gilteritinib 5Gemtuzumab 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Active not recruiting × Leukemia, Myeloid, Acute × Sorafenib × Clear all
NCT03164057 2026-04-23

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
206 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03132454 2026-04-15

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

M.D. Anderson Cancer Center

Phase 1 Active not recruiting
32 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01861314 2026-04-13

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

Phase 1 Active not recruiting
15 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03247088 2025-12-15

Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
74 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

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