Announcements Trials
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Phase

Phase 3 1

Status

Active not recruiting 1

Sponsor Class

OTHER 3NIH 2NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia 14Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Burkitt Lymphoma 5Lymphoma 3Leukemia, Biphenotypic, Acute 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Myelodysplastic Syndromes 2Down Syndrome 2Thrombocytopenia 1Optic Nerve Glioma 1Neutropenia 1Myelodysplastic-Myeloproliferative Diseases 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Acute 1Leukemia, Monocytic, Acute 1Leukemia, Eosinophilic, Acute 1Dendritic Cell Sarcoma, Interdigitating 1Central Nervous System Neoplasms 1Brain Neoplasms 1Astrocytoma 1Anemia, Refractory, with Excess of Blasts 1Anemia, Refractory 1

Interventions

Cytarabine 30Daunorubicin 15Gene Expression Profiling 9Gemtuzumab 9Flow Cytometry 9Idarubicin 8Mitoxantrone 7sargramostim 6fludarabine 6Polymerase Chain Reaction 6Methotrexate 6Filgrastim 6Etoposide 6Cyclophosphamide 6Busulfan 6fludarabine phosphate 5Specimen Handling 5merphos 4Whole-Body Irradiation 4Stem Cell Transplantation 4Peripheral Blood Stem Cell Transplantation 4Mycophenolic Acid 4Biopsy 4Tacrolimus 3Observation 3Melphalan 3Immunologic Techniques 3Hydrocortisone 3DNA Methylation 3Clofarabine 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NETWORK × Leukemia, Myeloid, Acute × Thioguanine × Clear all
NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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