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Phase

Phase 2 5Phase 3 3Phase 1 3Phase 1/2 1

Status

Completed 3Terminated 1Active not recruiting 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Other hematologic neoplasm 5Myeloid 1

Conditions

Leukemia, Myeloid, Acute 5Myelodysplastic Syndromes 2Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid 1Leukemia 1

Interventions

Cytarabine 197Azacitidine 143Cyclophosphamide 136fludarabine phosphate 112fludarabine 97Busulfan 96venetoclax 95Mycophenolic Acid 82Whole-Body Irradiation 81Tacrolimus 78Peripheral Blood Stem Cell Transplantation 78Decitabine 62Filgrastim 56Granulocyte Colony-Stimulating Factor 54Cyclosporine 53Melphalan 52Methotrexate 51Idarubicin 51Daunorubicin 49Antilymphocyte Serum 47Clofarabine 43Etoposide 41Thiotepa 35Gemtuzumab 34Mitoxantrone 32Stem Cell Transplantation 31CPX-351 27Specimen Handling 25Radiotherapy 25thymoglobulin 24

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Myeloid, Acute × glasdegib × Clear all
NCT03226418 2026-03-10

Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia

University of Nebraska

Phase 2 Completed
75 enrolled 14 charts
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT04231851 2026-03-06

CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia

University of California, Irvine

Phase 2 Active not recruiting
30 enrolled 15 charts
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01841333 2022-01-25

PF-04449913 For Patients With Acute Myeloid Leukemia at High Risk of Relapse After Donor Stem Cell Transplant

University of Colorado, Denver

Phase 2 Completed
31 enrolled 10 charts
Other hematologic neoplasm

Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT04051996 2021-10-15

GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia

Yale University

Phase 2 Terminated
1 enrolled 4 charts
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01546038 2020-03-03

A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Pfizer

Phase 2 Completed
255 enrolled 82 charts 1 FDA
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

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