Announcements Trials
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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 108Leukemia, Lymphocytic, Chronic, B-Cell 30Myelodysplastic Syndromes 23Leukemia, Biphenotypic, Acute 11Recurrence 10Lymphoma, Mantle-Cell 9Leukemia 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Leukemia, Myelomonocytic, Chronic 8Burkitt Lymphoma 8Waldenstrom Macroglobulinemia 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma, B-Cell, Marginal Zone 7Lymphoma 7Hematologic Neoplasms 7Neoplasms 6Lymphoma, Large B-Cell, Diffuse 6Myeloproliferative Disorders 5Lymphoma, Non-Hodgkin 5Lymphoma, Follicular 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Multiple Myeloma 3Anemia, Refractory, with Excess of Blasts 3Sarcoma, Myeloid 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, B-Cell 2Leukemia, Myeloid 2Immunoglobulin Light-chain Amyloidosis 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Blast Crisis 2

Interventions

Specimen Handling 2Biopsy 2Azacitidine 2venetoclax 1veliparib 1pevonedistat 1peginterferon alfa-2b 1fludarabine phosphate 1axatilimab 1Whole-Body Irradiation 1Topotecan 1Tacrolimus 1Sirolimus 1Peripheral Blood Stem Cell Transplantation 1Mycophenolic Acid 1Methotrexate 1Melphalan 1Hyperbaric Oxygenation 1Etoposide 1Cyclosporine 1Cyclophosphamide 1Carboplatin 1Busulfan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative × venetoclax × 90 days × Clear all
NCT03862157 2026-03-11

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
40 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytosis, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hypereosinophilic Syndrome, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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