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Phase

Phase 1 3Phase 2 2Phase 1/2 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 1Classical hematology 1

Conditions

Multiple Myeloma 188Lymphoma, Mantle-Cell 34Neoplasms, Plasma Cell 32Lymphoma 32Recurrence 26Lymphoma, Follicular 20Waldenstrom Macroglobulinemia 18Lymphoma, Non-Hodgkin 17Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, Large B-Cell, Diffuse 13Lymphoma, B-Cell, Marginal Zone 13Carcinoma, Non-Small-Cell Lung 13Immunoglobulin Light-chain Amyloidosis 10Neoplasms 9Leukemia, Myeloid, Acute 9Lymphoma, B-Cell 8Renal Insufficiency 7Leukemia, Lymphocytic, Chronic, B-Cell 7Leukemia 7Hodgkin Disease 6Lymphoma, T-Cell, Peripheral 5Lymphoma, T-Cell 5Prostatic Neoplasms 4Myelodysplastic Syndromes 4Kidney Neoplasms 4Carcinoma, Renal Cell 4Breast Neoplasms 4Brain Neoplasms 4Amyloidosis 4Stomach Neoplasms 3

Interventions

Cytarabine 30Filgrastim 12Daunorubicin 11Busulfan 11Idarubicin 10Peripheral Blood Stem Cell Transplantation 9Etoposide 9fludarabine phosphate 8Mitoxantrone 7Methotrexate 7Gemtuzumab 7sargramostim 6Cyclosporine 6Decitabine 5Cyclophosphamide 5Azacitidine 5Antilymphocyte Serum 5tipifarnib 4alvocidib 4Tacrolimus 4Whole-Body Irradiation 3Vorinostat 3Radiotherapy 3Mycophenolic Acid 3Injections 3Granulocyte Colony-Stimulating Factor 3Clofarabine 3Biopsy 3merphos 2entinostat 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Myelomonocytic, Acute × Bortezomib × Clear all
NCT00666588 2018-05-22

Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia

National Cancer Institute (NCI)

Phase 2 Completed
52 enrolled 17 charts
Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00818649 2017-12-28

Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Masonic Cancer Center, University of Minnesota

Phase 2 Terminated
16 enrolled 7 charts
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

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