Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Active not recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Plasma cell 1

Conditions

Myelodysplastic Syndromes 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Leukemia, Prolymphocytic, T-Cell 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Acute 2Hematologic Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Sarcoma, Synovial 1Sarcoma 1Primary Myelofibrosis 1Multiple Myeloma 1Melanoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Large B-Cell, Diffuse 1Liposarcoma, Myxoid 1Leukemia, Plasma Cell 1Leukemia 1Leiomyosarcoma 1Hodgkin Disease 1Histiocytoma, Malignant Fibrous 1Hematologic Diseases 1Gastrointestinal Neoplasms 1Chondrosarcoma 1Breast Neoplasms 1

Interventions

Cyclophosphamide 69fludarabine phosphate 66Peripheral Blood Stem Cell Transplantation 52Mycophenolic Acid 48Whole-Body Irradiation 47Tacrolimus 44Busulfan 43Cyclosporine 38Azacitidine 35Methotrexate 28Filgrastim 27Antilymphocyte Serum 27Cytarabine 26Decitabine 23Melphalan 22Radiotherapy 21fludarabine 20venetoclax 16Methylprednisolone 16Cyclosporins 13Cord Blood Stem Cell Transplantation 13Injections 12Granulocyte Colony-Stimulating Factor 12Flow Cytometry 12Specimen Handling 11Etoposide 11Biopsy 11Stem Cell Transplantation 10Sirolimus 10Clofarabine 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Leukemia, Myelomonocytic, Chronic × itacitinib × Clear all
NCT05364762 2026-06-03

Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

City of Hope Medical Center

Phase 2 Active not recruiting
20 enrolled
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT05823571 2025-09-18

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Active not recruiting
32 enrolled
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia, Leukemia, Plasma Cell, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Prolymphocytic, T-Cell, Leukemia, Myelomonocytic, Chronic

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