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Phase

Phase 3 1Phase 2 1Phase 1/2 1Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 4Myelodysplastic Syndromes 2Neoplasm, Residual 1Lung Neoplasms 1Leukemia, Myelomonocytic, Chronic 1Cholangiocarcinoma 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Hepatocellular 1

Interventions

Cyclophosphamide 46fludarabine phosphate 40Tacrolimus 36Busulfan 34Peripheral Blood Stem Cell Transplantation 31Whole-Body Irradiation 29Mycophenolic Acid 27Antilymphocyte Serum 23Methotrexate 22Azacitidine 21Cyclosporine 20Cytarabine 17Melphalan 16Decitabine 16Radiotherapy 14fludarabine 13Methylprednisolone 12Filgrastim 12Cord Blood Stem Cell Transplantation 10Stem Cell Transplantation 8Etoposide 8Biopsy 8venetoclax 7Specimen Handling 7Rituximab 7Injections 7Arsenic Trioxide 7thymoglobulin 6merphos 6Sirolimus 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Leukemia, Myelomonocytic, Chronic × pevonedistat × Clear all
NCT02610777 2022-09-19

An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)

Takeda

Phase 2 Completed
120 enrolled 39 charts
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

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