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Phase

Phase 2 1Phase 1/2 1

Status

Terminated 2Recruiting 2Completed 2Active not recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 8Primary Myelofibrosis 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Myeloproliferative Disorders 5Myelodysplastic Syndromes 5Thrombocythemia, Essential 4Recurrence 4Polycythemia Vera 4Multiple Myeloma 4Leukemia 4Lymphoma, T-Cell, Cutaneous 3Lymphoma, T-Cell 3Graft vs Host Disease 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, T-Cell, Peripheral 2Lymphoma 2Leukemia, Prolymphocytic, T-Cell 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Large Granular Lymphocytic 2Hematologic Neoplasms 2Triple Negative Breast Neoplasms 1Targeted Therapy 1Prostatic Neoplasms 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Neoplasms 1Neoplasm Metastasis 1Mycosis Fungoides 1Lymphoma, Non-Hodgkin 1Lymphoma, Large-Cell, Anaplastic 1

Interventions

Cyclophosphamide 11Azacitidine 10fludarabine 9Whole-Body Irradiation 9Specimen Handling 9Biopsy 9Stem Cell Transplantation 8Mycophenolic Acid 8venetoclax 7fludarabine phosphate 7Tacrolimus 6Cytarabine 6X-Rays 5Hematopoietic Stem Cell Transplantation 5Decitabine 4Cyclosporine 4Thiotepa 3Peripheral Blood Stem Cell Transplantation 3Melphalan 3Magnetic Resonance Spectroscopy 3Injections 3Idarubicin 3Granulocyte Colony-Stimulating Factor 3Filgrastim 3Cyclosporins 3Busulfan 311-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 3ruxolitinib 2pegylated granulocyte colony-stimulating factor 2olutasidenib 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recruiting × Leukemia, Myelomonocytic, Chronic × ruxolitinib × Clear all
NCT07128381 2026-01-05

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

M.D. Anderson Cancer Center

Phase 1/2 Recruiting
66 enrolled
MyeloidOther hematologic neoplasm

Leukemia, Myelomonocytic, Chronic, Primary Myelofibrosis

NCT07249346 2025-12-24

Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation

Ohio State University Comprehensive Cancer Center

Phase 2 Recruiting
124 enrolled
Classical hematologyOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Leukemia, Leukemia, Myelomonocytic, Chronic

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