Announcements Trials
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Phase

Phase 2 2

Status

Active not recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Sarcoma 1

Conditions

Lymphoma 32Precursor Cell Lymphoblastic Leukemia-Lymphoma 27Leukemia 26Lymphoma, Non-Hodgkin 18Sarcoma 17Leukemia, Myeloid, Acute 16Hematologic Neoplasms 12Neuroblastoma 11Neoplasms 11Myelodysplastic Syndromes 11Hodgkin Disease 11Leukemia, Myelogenous, Chronic, BCR-ABL Positive 9Leukemia, Lymphocytic, Chronic, B-Cell 9Breast Neoplasms 9Burkitt Lymphoma 8Osteosarcoma 6Multiple Myeloma 6Lymphoma, Large B-Cell, Diffuse 6Melanoma 5Lymphoma, Mantle-Cell 5Lymphoma, Follicular 5Rhabdoid Tumor 4Retinoblastoma 4Recurrence 4Neuroectodermal Tumors, Primitive, Peripheral 4Myeloproliferative Disorders 4Medulloblastoma 4Leukemia, Biphenotypic, Acute 4Leukemia, B-Cell 4Hematologic Diseases 4

Interventions

Cyclophosphamide 32fludarabine phosphate 30Mycophenolic Acid 24Busulfan 21Antilymphocyte Serum 20Tacrolimus 19Peripheral Blood Stem Cell Transplantation 18Methotrexate 18Melphalan 17Filgrastim 17Whole-Body Irradiation 15Cyclosporine 15thymoglobulin 11fludarabine 11Methylprednisolone 11Cytarabine 11Radiotherapy 10Thiotepa 8Granulocyte Colony-Stimulating Factor 8Cord Blood Stem Cell Transplantation 8Stem Cell Transplantation 7Etoposide 6Clofarabine 6Rituximab 5Azacitidine 5Transplantation 4Sirolimus 4Isotretinoin 4Flow Cytometry 4Antibodies 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Leukemia, Myelomonocytic, Juvenile × Mesna × Clear all
NCT03849651 2026-06-03

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
69 enrolled 17 charts
LymphoidMyeloidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT02790515 2025-08-12

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
170 enrolled
LymphoidMyeloidOther hematologic neoplasmSarcoma

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Sarcoma, Myeloid, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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