Announcements Trials
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Phase

Phase 2 2

Status

Active not recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Sarcoma 1

Conditions

Lymphoma 26Precursor Cell Lymphoblastic Leukemia-Lymphoma 21Leukemia 17Lymphoma, Non-Hodgkin 16Sarcoma 9Leukemia, Myeloid, Acute 9Hodgkin Disease 9Hematologic Neoplasms 9Neuroblastoma 8Neoplasms 8Myelodysplastic Syndromes 7Leukemia, Lymphocytic, Chronic, B-Cell 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6Burkitt Lymphoma 6Osteosarcoma 5Melanoma 5Lymphoma, Mantle-Cell 5Lymphoma, Follicular 5Breast Neoplasms 5Rhabdoid Tumor 4Retinoblastoma 4Multiple Myeloma 4Medulloblastoma 4Lymphoma, Large B-Cell, Diffuse 4Wilms Tumor 3Recurrence 3Neoplasms, Germ Cell and Embryonal 3Myeloproliferative Disorders 3Hepatoblastoma 3Graft vs Host Disease 3

Interventions

Cyclophosphamide 27fludarabine phosphate 26Mycophenolic Acid 22Tacrolimus 17Busulfan 17Antilymphocyte Serum 17Peripheral Blood Stem Cell Transplantation 16Whole-Body Irradiation 15Methotrexate 15Melphalan 15Filgrastim 15Cyclosporine 15thymoglobulin 10fludarabine 10Methylprednisolone 9Thiotepa 8Radiotherapy 8Stem Cell Transplantation 7Granulocyte Colony-Stimulating Factor 7Cytarabine 7Cord Blood Stem Cell Transplantation 7Etoposide 6Clofarabine 6Rituximab 5Sirolimus 4Antibodies 4Alemtuzumab 4Flow Cytometry 3Azacitidine 3merphos 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Leukemia, Myelomonocytic, Juvenile × Mesna × Clear all
NCT03849651 2026-06-03

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
69 enrolled 17 charts
LymphoidMyeloidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT02790515 2025-08-12

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
170 enrolled
LymphoidMyeloidOther hematologic neoplasmSarcoma

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Sarcoma, Myeloid, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

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