Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 17Terminated 6Active not recruiting 4Unknown 2Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1CNS 1

Conditions

Leukemia, Myeloid, Acute 17Precursor Cell Lymphoblastic Leukemia-Lymphoma 15Lymphoma, Non-Hodgkin 12Myelodysplastic Syndromes 11Recurrence 7Leukemia, Myelomonocytic, Chronic 7Anemia, Refractory, with Excess of Blasts 7Leukemia, Biphenotypic, Acute 6Multiple Myeloma 5Lymphoma, Follicular 5Lymphoma 5Hodgkin Disease 5Hematologic Neoplasms 5Melanoma 4Lymphoma, Large B-Cell, Diffuse 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Burkitt Lymphoma 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myeloproliferative Disorders 3Lymphoma, Mantle-Cell 3Lymphoma, B-Cell, Marginal Zone 3Lymphoma, B-Cell 3Leukemia, Lymphocytic, Chronic, B-Cell 3Leukemia 3Breast Neoplasms 3Blastic Plasmacytoid Dendritic Cell Neoplasm 3Uveal Melanoma 2Triple Negative Breast Neoplasms 2Neoplasms, Plasma Cell 2Neoplasms, Germ Cell and Embryonal 2

Interventions

fludarabine 4Specimen Handling 2Cytarabine 2Cyclophosphamide 2trametinib 1thymoglobulin 1merphos 1imetelstat 1hydrocortisone hemisuccinate 1fludarabine phosphate 1Watchful Waiting 1Spinal Puncture 1Rituximab 1Methotrexate 1Melphalan 1Levetiracetam 1Leucovorin 1Injections 1Hydrocortisone 1Hematopoietic Stem Cell Transplantation 1GRN163L peptide 1Busulfan 1Biopsy 1Azacitidine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Leukemia, Myelomonocytic, Juvenile × fludarabine phosphate × Clear all
NCT05849662 2026-04-15

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1/2 Recruiting
58 enrolled
CNSOther hematologic neoplasm

Neurofibromatosis 1, Leukemia, Myelomonocytic, Juvenile

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