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Phase

Phase EARLY_PHASE1 1Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Leukemia, Myeloid, Acute 66Myelodysplastic Syndromes 38Leukemia, Myelomonocytic, Chronic 26Leukemia 14Myeloproliferative Disorders 10Recurrence 7Lymphoma 7Hematologic Neoplasms 7Neoplasms 6Primary Myelofibrosis 5Multiple Myeloma 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasm, Residual 3Myelodysplastic-Myeloproliferative Diseases 3Lymphoma, T-Cell, Peripheral 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Colorectal Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Prostatic Neoplasms 2Pancreatic Neoplasms 2Neoplasm Metastasis 2Melanoma 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Leukemia, Megakaryoblastic, Acute 2Leukemia, Erythroblastic, Acute 2Glioblastoma 2Carcinoma, Renal Cell 2Anemia, Refractory, with Excess of Blasts 2

Interventions

Methotrexate 5Peripheral Blood Stem Cell Transplantation 4Cyclosporine 4Busulfan 4fludarabine phosphate 2Whole-Body Irradiation 2Tacrolimus 2Mycophenolic Acid 2Cyclophosphamide 2Antilymphocyte Serum 2venetoclax 1pevonedistat 1ethanolamine oleate 1Trimethoprim, Sulfamethoxazole Drug Combination 1Trimethoprim 1Sulfamethoxazole 1Sodium Chloride 1Sirolimus 1Saline Solution, Hypertonic 1Saline Solution 1Phenytoin 1Pentostatin 1Pentetic Acid 1In Situ Hybridization, Fluorescence 1Immunoenzyme Techniques 1Granulocyte Colony-Stimulating Factor 1Flow Cytometry 1Ethanol 1Edetic Acid 1Cytogenetic Analysis 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Leukemia, Neutrophilic, Chronic × Azacitidine × Clear all
NCT03862157 2026-03-11

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
40 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytosis, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hypereosinophilic Syndrome, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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