Announcements Trials
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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell 22Lymphoma, Mantle-Cell 13Lymphoma, Non-Hodgkin 10Lymphoma, Large B-Cell, Diffuse 10Waldenstrom Macroglobulinemia 7Lymphoma, Follicular 7Lymphoma, B-Cell, Marginal Zone 5Lymphoma 5Neoplasms 4Leukemia, B-Cell 4Lymphoma, B-Cell 3Burkitt Lymphoma 3Recurrence 2Leukemia, Prolymphocytic 2Leukemia, Lymphoid 2Leukemia, Hairy Cell 2Leukemia 2Hematologic Diseases 2Bronchiolitis Obliterans Syndrome 2Squamous Cell Carcinoma of Head and Neck 1Prostatic Neoplasms, Castration-Resistant 1Primary Central Nervous System Lymphoma (PCNSL) 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Myelodysplastic Syndromes 1Multiple Myeloma 1Melanoma 1Lymphoproliferative Disorders 1Lymphoma, AIDS-Related 1Lymphatic Diseases 1Leukemia, Prolymphocytic, B-Cell 1

Interventions

pevonedistat 1ibrutinib 1fludarabine phosphate 1Specimen Handling 1Pharmacogenomic Variants 1Leukapheresis 1Cyclophosphamide 1Blood Component Removal 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Leukemia, Prolymphocytic, B-Cell × ibrutinib × 90 days × Clear all
NCT03479268 2026-04-27

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

City of Hope Medical Center

Phase 1 Active not recruiting
18 enrolled
LymphoidOther hematologic neoplasm

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Prolymphocytic, B-Cell

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