Announcements Trials
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Phase

Phase 1 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell 23Lymphoma, Mantle-Cell 14Lymphoma, Non-Hodgkin 6Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Follicular 6Lymphoma, B-Cell, Marginal Zone 5Waldenstrom Macroglobulinemia 4Lymphoma, B-Cell 4Lymphoma 4Leukemia, B-Cell 4Leukemia 3Neoplasms 2Melanoma 2Leukemia, Prolymphocytic 2Recurrence 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neurologic Manifestations 1Myeloproliferative Disorders 1Lymphoma, AIDS-Related 1Leukemia, Prolymphocytic, B-Cell 1Leukemia, Lymphoid 1Leukemia, Hairy Cell 1Hematologic Diseases 1Graft vs Host Disease 1Glioblastoma 1Disease Progression 1Central Nervous System Neoplasms 1Cardiovascular Diseases 1Burkitt Lymphoma 1Breast Neoplasms 1

Interventions

pevonedistat 1ibrutinib 1fludarabine phosphate 1Pharmacogenomic Variants 1Etoposide 1Cyclophosphamide 1Bendamustine Hydrochloride 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Active not recruiting × Leukemia, Prolymphocytic, B-Cell × ibrutinib × Clear all
NCT03479268 2026-04-27

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

City of Hope Medical Center

Phase 1 Active not recruiting
18 enrolled
LymphoidOther hematologic neoplasm

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Prolymphocytic, B-Cell

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