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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1Classical hematology 1

Conditions

Leukemia 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Leukemia, Myeloid, Acute 5Congenital Abnormalities 5Lymphoma 4Leukemia, Lymphocytic, Chronic, B-Cell 4Hodgkin Disease 4Myelodysplastic Syndromes 3Lymphoma, Large B-Cell, Diffuse 3Leukemia, Myelomonocytic, Chronic 3Sezary Syndrome 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Myelodysplastic-Myeloproliferative Diseases 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Follicular 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Intraocular Lymphoma 2Immunoblastic Lymphadenopathy 2Burkitt Lymphoma 2Blast Crisis 2Anemia, Refractory, with Excess of Blasts 2Small Cell Lung Carcinoma 1Optic Nerve Glioma 1

Interventions

fludarabine phosphate 29Cyclophosphamide 18Mycophenolic Acid 17Whole-Body Irradiation 16Peripheral Blood Stem Cell Transplantation 16Cyclosporine 13Antilymphocyte Serum 9Tacrolimus 8Cyclosporins 8fludarabine 7Rituximab 7Busulfan 7Filgrastim 6Sirolimus 4Methotrexate 4Cytarabine 4Thiotepa 3Therapeutics 3Melphalan 3Lenalidomide 3Granulocyte Colony-Stimulating Factor 3Etoposide 3Epoetin Alfa 3Darbepoetin alfa 3Cord Blood Stem Cell Transplantation 3Carboplatin 3Allopurinol 3pegfilgrastim 2liposomal amphotericin B 2Radiotherapy 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Leukemia, Prolymphocytic × laromustine × Clear all
NCT00049686 2013-07-18

VNP40101M in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 1 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Leukemia, Leukemia, Hairy Cell, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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