Clinical Trials

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT06870760 2026-04-16

Pre-malignant States to Hematologic Malignancies in Firefighters

300 enrolled

Classical hematologyLymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Non-Hodgkin, Multiple Myeloma, Paraproteinemias, Neoplasms, Plasma Cell

NCT06839456 2026-04-15

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Phase 1/2 Recruiting

100 enrolled

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Anemia, Refractory, with Excess of Blasts, Hemoglobinopathies, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Non-Hodgkin, Metabolism, Inborn Errors

NCT07356245 2026-04-15

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

Phase 2 Recruiting

44 enrolled

DermatologicLymphoidOther hematologic neoplasm

Graft vs Host Disease, Leukemia, Lymphoma, Leukemia, Prolymphocytic, T-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT04547049 2026-04-09

A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

Phase 3 Active not recruiting

232 enrolled

Leukemia

NCT06021600 2026-04-09

A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribine

Phase 1 Terminated

3 enrolled

Phase 1 Not yet recruiting

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT07518654 2026-04-08

ThINKK-01

12 enrolled

CNSLymphoidOther hematologic neoplasm

Paroxysmal nonkinesigenic dyskinesia, Leukemia, Neoplasm Metastasis, Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03467867 2026-04-06

A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL

25 enrolled

Leukemia, Lymphoproliferative Disorders, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell

NCT06056908 2026-04-06

SDSR

Classical hematologyOther hematologic neoplasm

5,000 enrolled

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Shwachman-Diamond Syndrome, Leukemia, Neutropenia

NCT07512882 2026-04-06

MYELOMONO-3

5,000 enrolled

Leukemia, Leukemia, Myelomonocytic, Chronic

NCT04024761 2026-04-03

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

50 enrolled

Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Juvenile

NCT05544968 2026-04-03

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

42 enrolled

Hodgkin Disease, Leukemia, Lymphoma, Neoplasms, Recurrence, Lymphoma, Large-Cell, Anaplastic

NCT03722407 2026-04-02

Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion

29 enrolled 11 charts

Leukemia, Leukemia, Myelomonocytic, Chronic

NCT05763563 2026-03-31

Exercise Prehabilitation Among Older Patients With Hematological Malignancies Preparing For CAR-T Cell Immunotherapy

Phase NA Completed

20 enrolled

Leukemia, Lymphoma, Neoplasms, Plasma Cell

NCT04747912 2026-03-30

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

Phase 2 Suspended

25 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03793140 2026-03-27

A Study of CPI-613 for Patients With Relapsed or Refractory Burkitt Lymphoma/Leukemia or High-Grade B-Cell Lymphoma With High-Risk Translocations

24 enrolled

Burkitt Lymphoma, Leukemia, Lymphoma

NCT04307576 2026-03-27

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Phase 3 Recruiting

6,430 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05237245 2026-03-25

HTLV-OBS

Active not recruiting

69 enrolled

Leukemia, Lymphoma, HTLV-I Infections

NCT06313437 2026-03-25

Revumenib in Combination With 7+3 + Midostaurin in AML

22 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT00576979 2026-03-24

Intensity-Modulated Radiation Therapy, Etoposide, and Cyclophosphamide Followed By Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Phase 1/2 Completed

51 enrolled 16 charts

LymphoidMyeloidOther hematologic neoplasm

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05969821 2026-03-23

CHIS

Not yet recruiting

5,000 enrolled

VEXAS syndrome, Autoimmune Diseases, Hematologic Diseases, Immune System Diseases, Inflammation, Leukemia, Lymphoma, Lymphoproliferative Disorders, Monoclonal Gammopathy of Undetermined Significance, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases

NCT07292272 2026-03-23

Halt Aging in Survivors of Blood Cancers: the HALTAging-1 Study

Phase 2 Not yet recruiting

180 enrolled

Hodgkin Disease, Leukemia, Leukemia, Lymphoid, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Lymphoma, Non-Hodgkin, Multiple Myeloma

NCT01315132 2026-03-19

A Study of Bone Marrow Transplantation Using Fully-Matched Relatives as Donors for Patients With Hematological Malignancies

Phase 2 Completed

47 enrolled 8 charts

Hodgkin Disease, Leukemia, Lymphoma, Multiple Myeloma, Hematologic Neoplasms

NCT07483749 2026-03-19

HEM-SURVIVE: Structuralized Follow-up for Childhood Hematological Malignancy Survivors

Not yet recruiting

400 enrolled

Leukemia, Lymphoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06152809 2026-03-18

CIML NK Cells With Venetoclax for AML

10 enrolled

Phase 1 Not yet recruiting

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT07464951 2026-03-11

CART123

30 enrolled

Phase EARLY_PHASE1 Recruiting

Leukemia, Leukemia, Myeloid, Acute

NCT06890494 2026-03-10

Clinical Study on the Safety and Efficacy of BiTE-EV in Relapsed/Refractory Acute B-Cell Leukemia

3 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia

NCT01758042 2026-03-06

BMT

Phase NA Completed

10 enrolled

Immunoglobulin Light-chain Amyloidosis, Anemia, Aplastic, Anemia, Sickle Cell, Autoimmune Diseases, Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Thalassemia, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Anemia, Diamond-Blackfan, Renal Insufficiency, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT07060001 2026-03-06

Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker

Phase 2 Not yet recruiting

112 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT02530463 2026-03-05

Nivolumab and/or Ipilimumab With or Without Azacitidine in Treating Patients With Myelodysplastic Syndrome

99 enrolled

Leukemia, Myelodysplastic Syndromes

NCT05268003 2026-03-05

A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia

26 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07450872 2026-03-05

SC-Het-GM-CCS

CNSOther hematologic neoplasm

600 enrolled

Glioma, Leukemia, Neoplasms, Syndrome, Leukemia, Myeloid, Acute

NCT07044544 2026-03-04

Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies

20 enrolled

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT07294677 2026-03-04

CAVALRY

Phase 1/2 Recruiting

104 enrolled

Leukemia, Lymphoma

NCT07405424 2026-03-04

Spiritual Care Intervention in Adult Patients Diagnosed With Acute Leukemia

Phase NA Recruiting

70 enrolled

Leukemia

NCT02975869 2026-03-03

A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia

Phase NA Completed

160 enrolled

Phase 1 Not yet recruiting

Leukemia, Leukemia, Myeloid, Acute

NCT07439211 2026-03-03

GAVEL

48 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT03514017 2026-03-02

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Phase 2 Terminated

5 enrolled 11 charts

BreastLymphoidOther hematologic neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT03953326 2026-02-27

HeartPhone Cancer Survivors Trial 2019

Phase 1/2 Terminated

2 enrolled 6 charts

Breast Neoplasms, Leukemia, Lymphoma

NCT03609593 2026-02-25

Bendamustine/Rituximab Followed by Venetoclax and Rituximab for Treatment of Chronic Lymphocytic Leukemia

Phase 2 Completed

42 enrolled

Phase 1 Active not recruiting

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT03974217 2026-02-25

Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts

13 enrolled

Leukemia

NCT05536349 2026-02-24

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

Phase 2 Recruiting

60 enrolled

Leukemia

NCT06522373 2026-02-24

Phase I Trial of MT-0169 in CD38+ Acute Leukemia With Relapsed/Refractory or Measurable Residual Disease

Phase 1 Withdrawn

Phase EARLY_PHASE1 Recruiting

Leukemia

NCT07429461 2026-02-24

Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia

16 enrolled

Phase EARLY_PHASE1 Recruiting

Burkitt Lymphoma, Leukemia

NCT02356653 2026-02-20

ExpMACs

100 enrolled