Clinical Trials

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03263936 2025-10-16

Epigenetic Reprogramming in Relapse/Refractory AML

37 enrolled 11 charts

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT05645718 2025-10-07

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Phase 2 Recruiting

27 enrolled

Phase 2 Active not recruiting

Leukemia

NCT01920737 2025-09-16

A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia

39 enrolled

Leukemia

NCT05658640 2025-09-16

HEM-iSMART D

Phase 1/2 Recruiting

26 enrolled

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05745714 2025-09-16

HEM-iSMART C

Phase 1/2 Recruiting

26 enrolled

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05751044 2025-09-16

HEM-iSMART B

Phase 1/2 Recruiting

26 enrolled

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00410423 2025-04-30

Study of VELCADE® With Mitoxantrone and Etoposide for Leukemias

Phase 1/2 Completed

55 enrolled 9 charts

OtherOther hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01085617 2025-03-30

UKALL14

Completed

Leukemia, Mucositis

NCT03654716 2025-02-14

Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer

CNSLymphoidOther hematologic neoplasm

21 enrolled

Brain Neoplasms, Leukemia, Lymphoma

NCT01228331 2024-12-11

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL

Phase 2/3 Completed

745 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06643962 2024-11-12

Venetoclax Combined with Intensive Therapy for Acute Myeloid Leukemia Patients with Lower Early Peripheral Blast Clearance Rate After Standard Induction Therapy

Phase NA Recruiting

83 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT02441803 2024-02-22

Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)

11 enrolled 12 charts

Leukemia, Leukemia, Myeloid, Acute

NCT01186328 2024-02-01

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Phase 1 Terminated

6 enrolled 11 charts

Leukemia, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT03904251 2023-11-18

CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia

Phase 1 Terminated

13 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT00039130 2023-08-21

Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia

105 enrolled 8 charts

Burkitt Lymphoma, Leukemia, Lymphoma

NCT01614197 2023-07-27

A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma

16 enrolled 16 charts

Leukemia, Recurrence, Lymphoma, T-Cell, Peripheral, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04687098 2023-06-27

Risk-adapted Therapy for Primary Acute Myeloid Leukemia

1,034 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT02280525 2023-06-07

Cord Blood Natural Killer (NK) Cells in Leukemia/Lymphoma

8 enrolled

Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT02891278 2023-04-12

Sertraline and Cytosine Arabinoside in Adults With Relapsed and Refractory AML

6 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT04688021 2023-02-21

A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.

Phase 2 Unknown

46 enrolled

MyeloidOther hematologic neoplasm

Graft vs Host Disease, Leukemia

NCT00003407 2023-02-02

Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML

Phase 2 Withdrawn

Blast Crisis, Leukemia, Myelodysplastic Syndromes, Neutropenia, Leukemia, Myeloid, Acute, Drug-Related Side Effects and Adverse Reactions

NCT01005914 2023-01-06

Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 2 Terminated

11 enrolled 6 charts

Leukemia, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01154439 2022-10-26

AML1208

11 enrolled

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT02403310 2022-10-03

A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML

21 enrolled

Chromosome Aberrations, Leukemia, Leukemia, Myeloid, Acute

NCT01700946 2022-09-28

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

80 enrolled 13 charts

Leukemia, Lymphoma

NCT01319981 2022-09-27

Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

31 enrolled 9 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00549848 2022-08-23

Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

Phase 3 Completed

600 enrolled 16 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03988205 2022-07-19

Patients Receiving Induction With Liposomal Daunorubicin and Cytarabine (CPX-351) for Acute Myeloid Leukemia

Phase 4 Terminated

3 enrolled 10 charts

Leukemia, Leukemia, Myeloid, Acute

NCT01117441 2022-05-24

International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia

Phase 3 Completed

6,136 enrolled

Leukemia

NCT01411267 2022-04-04

AC220 for Children With Relapsed/Refractory ALL or AML

24 enrolled 14 charts

Leukemia, Leukemia, Myeloid, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04722952 2021-12-03

PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine，Cytarabine, G-CSF for Refractory or Relapsed AML

Phase 3 Unknown

30 enrolled

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT01246752 2021-10-29

AML

Phase 3 Terminated

143 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT00003405 2021-10-14

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia

Phase 2 Withdrawn

MyeloidOther hematologic neoplasm

Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT02464657 2021-10-07

Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Phase 1/2 Completed

44 enrolled 12 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01156883 2021-09-13

LAL1308

Phase NA Completed

76 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00558519 2021-08-18

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 2 Unknown

318 enrolled 9 charts

Leukemia

NCT00651261 2021-08-18

Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Phase 3 Unknown

717 enrolled 14 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01861002 2021-06-09

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

15 enrolled 10 charts

Leukemia, Leukemia, Myeloid, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00671658 2020-12-03

Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia

220 enrolled 6 charts