Clinical Trials

Leukemia, Recurrence, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05740449 2024-06-21

HEM-iSMART A

Phase 1/2 Withdrawn

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02441803 2024-02-22

Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)

11 enrolled 12 charts

Leukemia, Leukemia, Myeloid, Acute

NCT01893320 2022-02-09

Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

66 enrolled 10 charts

Leukemia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT01720225 2020-12-24

Decitabine Versus Azacitidine in Myelodysplastic Syndrome Patients With Low and Intermediate-1 Risk

113 enrolled 10 charts

Leukemia, Myelodysplastic Syndromes

NCT01483690 2020-10-27

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Phase 1/2 Terminated

23 enrolled 13 charts

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01498445 2020-10-22

An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357)

Phase 1/2 Terminated

32 enrolled 16 charts

Blast Crisis, Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT01786343 2020-04-15

Decitabine for Older or Unfit Patients With Acute Myeloid Leukemia (AML)

74 enrolled 11 charts

Leukemia, Leukemia, Myeloid, Acute

NCT02010645 2020-01-02

Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS)

Phase 2 Terminated

6 enrolled 8 charts

Leukemia, Leukemia, Myelomonocytic, Chronic

NCT01794702 2019-05-30

Decitabine Followed by Clofarabine, Idarubicin, and Cytarabine in Acute Leukemia

65 enrolled 12 charts

Leukemia, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03799224 2019-05-29

Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemia

Phase 2/3 Unknown

55 enrolled

Leukemia

NCT00075010 2018-11-15

Phase I/II Study of Decitabine and Valproic Acid in Relapsed/Refractory Leukemia or Myelodysplastic Syndromes

54 enrolled

Leukemia, Myelodysplastic Syndromes

NCT00903760 2018-11-15

Decitabine and Clofarabine in Higher Risk Myelodysplastic Syndromes (MDS)

42 enrolled 10 charts

Leukemia, Myelodysplastic Syndromes

NCT00002831 2018-10-26

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia

24 enrolled

Blast Crisis, Leukemia, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute

NCT02469415 2018-10-16

Pacritinib for Patients With Lower-Risk Myelodysplastic Syndromes (MDS)

Phase 2 Terminated

3 enrolled 6 charts

Leukemia, Myelodysplastic Syndromes

NCT01352650 2018-07-02

Decitabine and Plerixafor in Elderly Acute Myeloid Leukemia (AML)

71 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT02141477 2018-02-13

Omacetaxine and Decitabine in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Phase 1 Terminated

2 enrolled

Leukemia, Leukemia, Myeloid, Acute

NCT00882206 2017-12-28

Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

Phase 2 Terminated

15 enrolled 8 charts

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02234037 2017-01-30

Physical Conditioning and Decitabine for Newly Diagnosed AML Patients Age ≥ 60

Phase 1 Terminated

3 enrolled

Leukemia

NCT02084563 2016-11-08

Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms

Classical hematologyMyeloidOther hematologic neoplasm

455 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Primary Myelofibrosis

NCT00778375 2016-07-14

Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)

122 enrolled 10 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00479232 2015-09-21

Phase I Trial of Vorinostat (MK-0683, SAHA) in Combination With Decitabine in Patients With AML or MDS (MK-0683-055 EXT1)

71 enrolled 9 charts

Leukemia, Myelodysplastic Syndromes

NCT00882102 2013-09-13

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (H-R MDS)

43 enrolled 5 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00003361 2013-06-26

Decitabine in Treating Patients With Myelodysplastic Syndrome

Classical hematologyMyeloidOther hematologic neoplasm

75 enrolled

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00671697 2013-06-04

Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia

13 enrolled

Leukemia, Myelodysplastic Syndromes

NCT00968071 2013-03-08

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

71 enrolled 5 charts

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00002980 2013-02-15

Decitabine in Treating Patients With Melanoma or Other Advanced Cancer

LymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cell

Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Precancerous Conditions, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Primary Myelofibrosis

NCT00114257 2013-02-11

Decitabine and FR901228 in Treating Patients With Relapsed or Refractory Leukemia, Myelodysplastic Syndromes, or Myeloproliferative Disorders

LymphoidMyeloidOther hematologic neoplasm

36 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00002832 2012-07-30

Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia

LymphoidMyeloidOther hematologic neoplasm

14 enrolled

Blast Crisis, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01378416 2011-07-12

Pharmacokinetic Trial of Decitabine (Dacogen) Administered as a 3-hour Infusion to Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

16 enrolled 10 charts